The Recent Developments of the Study About The Relationship Among Matrix Metalloproteases Tissue Inhibitor of Metalloproteinases and Cerebral Ischemia or Reperfusion Injury
CHANG Huan-xian~1,LI Xiao-gang~2. (1.Luzhou Medical College,Luzhou 646000,China;2.Department of Neurology,The Affiliated Hospital of Luzhou Medical College,Luzhou 646000,China)
The study of middle cerebral artery occlusion and reperfusion on experimental animal model shows that matrix metalloproteases has an abnormal expression in cerebral ischemic and reperfusion.which indicates that MMPs is related to cerebral ischemic and reperfusion injury.Tissue inhibitor of metalloproteinases can inhibit the activity of MMPs,so the using of TIMPs can be a new method to treat the ischemic cerebrovascular diseases.
【CateGory Index】： R743