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《Medical Recapitulate》 2006-12
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The Significance about Intervention of Aldosterone′s Escape in Cardiovascular Diseases

ZHANG Li-ming,LIU Xin-lin,SHI Ru-hai.(The 535 Hospital of PLA,Huaihua 418008,China)  
The phenomenon of aldosterone escape means that its serum level will decrease in short time and then increase in long time during the application of ACEI.Its synthesis and releasing is also increased in chronic heart failure.Sodium retention,electrolyte disturbances,lipid collage deposition and fibrosis will result in progressive aggravation of chronic heart failure.Chemical constitution of aldoctone is similar to that of aldosterone which can inhibit its effect,decrease the total case fatality and /or length of stay of the heart failure and inhibit arrhythmia.The new selective adosterone antagonists can be a high recommended indication medicine in heart failure,hypertension and post-infarction of myocardium.
【CateGory Index】: R54
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【Citations】
Chinese Journal Full-text Database 1 Hits
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【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Department of Cardiology, Huaibei Hospital Of Traditional Chinese Medicine, Anhui 235000, China WANG Zheng- zhong, LIU Cheng;Clinical observation of spironolactone treatment in patients with chronic heart failure of coronary heart disease[J];Journal of Anhui Health Vocational & Technical College;2004-06
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【Co-references】
Chinese Journal Full-text Database 2 Hits
1 FU Hongli1, FANG Zhenying2 (1.Department of Cardiology,Taiyuan Municipal People’s Hospital, Taiyuan 030001, China; 2.Department of Cardiology,Shanxi Provincial Cardiovascular Diseases Hospital, Taiyuan 030024, China);Aldosterone Escape and Cardiovascular Diseases[J];Advances In Cardiovascular Diseases;2004-06
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【Secondary Citations】
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1 LIU Guo-hua (Department of Cardiology,the First Hospital of Xiangfan Hubei Province,441000);The renin-angiotensin-aldosterone activity in patients with heart failure of different blood pressure[J];JOURNAL OF CLINICAL CARDIOLOGY;2000-09
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