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Progress of Nuclear Factor decoy and its Antineoplastic Activity

SONG Shu-ya.(School of Clinical Medicine,Weifang Medical College,Weifang 261042,China)  
Neclear factor decoy technique is applying high affinity oligonucleotide to transfect cell,which was man-made and high identical to cis-acting element binded by transcription factor,for the competitive inhibition of transcription factor,which then results in gene expression inhibition by disability of transcription factors to interact with its endogenous gene or separation from its site of action in order to achieve gene therapy and gene regulation.This article reviews the progress of its antineoplastic activity.
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