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《Medical Recapitulate》 2006-24
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Therapeutic and diagnositic progress of Lupus Nephritis

YU Wen-jie.(The Department of Nephrology,The Third Central Hospital of Tian jin,Tinajin 300170,China)  
The clinical features of lupus nephritis(LN) is varied.Renal biopsy is significant for the clinicians to select treatment and evaluate prognosis.WHO remodified the classification of LN in 2003.The renal histopathologic changes is the main basis of selecting the appropriate treatment.Among the pathologic classification of LN,the prognosis of diffuse proliferative LN and focal proliferative LN(WHO class Ⅲ),with the involvment of more than 50 glomerulus is the worst.Corticosteroids and immunosuppressive therapy are still the preferred therapy for LN.Then Ⅳ r-globulin can be used as transitional therapy.Other therapies includes synchronous plasmapheresis,immunoabsorptin and HSCT,these are all have clinical foreground in a certain extent.
【CateGory Index】: R593.242
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