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《Medical Recapitulate》 2017-02
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Clinical Effect of Compound Anisodine Alkali Treatment of Ocular Fundus and Its Impact on Vision

ZHAO Shuai;YIN Ni;Department of Ophthalmology,Xi'an First Hospital;  
Objective To investigate the clinical efficacy of the compound anisodine treatment of ocular fundus and its impact on the patient's vision. Methods A total of 80 cases of ocular fundus in Xi' an First Hospital from Mar. 2014 to Mar. 2015 were included in the study,according to the sortation method they were divided into a control group and an observation group,40 cases in each group. The control group received conventional drug treatment( subcutaneous injection 2 mL,1 time per day,for 14 days continuously),the observation group was given joint use of compound anisodine treatment on the basis of the control group' s regimen. The hemodynamics indexes[blood viscosity( WBV),erythrocyte aggregation index( RAI),the erythrocyte hematocrit( HCT),fibrinogen( FIB) ] and vision changes,efficacy and relapse,adverse reactions( dry mouth,nausea,fatigue and chest tightness) of the two groups after treatment were observed. Results After treatment,the WBV,RAI,HCT,FIB of the observation group were significantly lower than those of the control group[( 4. 54 ±0. 31) mPa·s vs( 4. 76 ± 0. 33) mPa·s,4. 12 ± 0. 30 vs 4. 41 ± 0. 31,0. 34 ± 0. 03 vs 0. 41 ± 0. 02,( 2. 87 ± 0. 43) g / L vs( 3. 45 ± 0. 41) g / L]( P 0. 05); the mild low vision rate of the observation group was significantly higher than that of the control group[77. 5%( 31 /40) vs 77. 5%( 22 /40) ]( P 0. 05); Efficacy of the observation group was significantly higher than that of the control group[95. 0%( 38 /42) vs 80. 0%( 32 /40) ],and the recurrence rate was lower than the control group [2. 5%( 1 /40) vs 2. 5%( 6 /40) ]( P 0. 05); the total adverse reaction rate of the two groups had no statistically significant difference( P 0. 05). Conclusion The clinical efficacy of compound anisodine is affirmative for the treatment of ocular fundus,with low recurrence rate,which can significantly improve blood circulation,improve vision,and help patients recover,thus is worthy of application and promotion.
【CateGory Index】: R773
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