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Progress in the methodology on mutation research

Zhang Liming and Yin Muquan Second Military Medical University,Shanghai 200433 Xue Jinglun Fudan University,Shanghai 200433  
Gene mutations have been implicated in the aetiology of cancer,developmental anomalies,genetic disease,ageing and evolution.Many methods have been developed on mutation research.In this paper,the relationship between gene mutation and the methodology on mutation research was discussed.
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