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《China Pharmaceuticals》 2004-04
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The Experiment Research of Panax Notoginside on the Pulmonary Fibrosis

Li Xuejun 1 ,Cui Shehuai 2(1.Department of Respiration,Southwest Hospital,Third Military Medical University,Chongqing,China400038;2.Department of Respiration,Daping Hospital,Third Military Medical University,Chongqing,China400042)  
Objective:To study the effects of panax notoginside(PNS)on the developm e nt of pulmonary fibrosis.Methods:Rats were divided into3groups:control group ,pulmonary fibrosis group and PNS group.On days1,3,7,14,28after tre atment,5rats in each group were killed and the bronchial alveolar fluid(BALF ),lungs and plasma were harvested for detecting the cellular contents,histopa thologic studies,immunohistochemical determination of collagenⅠandⅢand ELISA detection of MIP-1 content of inflammatory cells(con tain eosinophils)in BALF was significantly lower than that of model group,and the degree of fibrosis.The levels of collagenⅠandⅢ,and the levels of MIP-1 significantly in the PNS group compared with fibrosis group (P0.01).Conclusion:PNS is an effective drug to inhibit the progress of fibrosis induced by bleomycin in rats and it can decrease the exudation of eosi nophils.
【CateGory Index】: R285
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【References】
Chinese Journal Full-text Database 5 Hits
1 ;The pharmacological progress on treatment for pulmonary fibrosis by Chinese herbs[J];Acta Academiae Medicinae Cpapf;2005-06
2 CAI Hong,LI Mei,QU Hao,TU Li-ping,CHEN Lan,CHEN Yang(Guizhou Provincial People's Hospital,Guiyang 550002,Guizhou,China);Influence of total saponins panax notoginseng on CD14 and TLR4 of mononuclear cell in acute cerebral infarct patients[J];Modern Journal of Integrated Traditional Chinese and Western Medicine;2007-08
3 QUAN Yan, XIA Qian - ming, LI Fu - xiang, LI Hong - yan, XIAO Zhen - liang 1:Department of Respiratory Diseases, General Hospital of Chengdu Military Co mmand, Chengdu, 610083.;Effect of Panax Notoginsenosides on pulmonary fibrosis induced by bleomycin in rats[J];Medicial Journal of National Defending Forces in Southwest China;2005-03
4 QUAN Yan,XIA Qian-ming,LI Fu-xiang,LI Hong-yan,ZHANG Ding-tao Department of Respiratory Disease,General Hospital of Chengdu Military Command,Chengdu,610083,China.;Effects of panax notoginsenosides on pulmonary fibrosis and CTGF expression in rats[J];Medical Journal of National Defending Forces in Southwest China;2009-01
5 GUO Ming-li~(1), WANG You-qun~(1*), CHEN Yong-he~(2)(1.Division of Pharmacology, China Pharmaceutical University,Nanjing 210009, China;2.Central Hospital of Pukou District,Nanjing 211800, China);The Effects and Mechanisms of Salvia Miltiorrhizae and Radix Notoginseng on Fibrosis of Organs in Diabetic Mice[J];Progress In Pharmaceutical Sciences;2005-06
【Citations】
Chinese Journal Full-text Database 1 Hits
1 Zheng Jinxu, Jia Youming *, Xu Zhude ** , Zhuang Li ** , Zhang Yue'e ** (Department of Pulmonary Diseases, Affiliated Hospital of Zhenjiang Medical College, Zhenjiang 212001; *Department of Pulmonary Diseases, Zhongshan Hospital and;CLINICAL SIGNIFICANCE OF COLLAGEN TYPING IN LUNG SPECIMENS FROM PATIATS WITH IDIOPATHIC PULMONARY FIBROSIS[J];JOURNAL OF SHANGHAI MEDICA(UNIVERSITY);1998-06
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 SUN Jian-guang (Shandong University of TCM,Jinan 250014,China);Discussion on method of tonifying the kidney and removing blood stasis for hepatocirrhosis[J];Shandong Journal of Traditional Chinese Medicine;2004-08
2 Lin Shou-ning,Huang Gui-hua,Wang Zhen-Changi;The Study of Zhuangganzhuyu Jian on Serum Markers in the Model of Liver Fibrosis.[J];Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine;2004-01
3 Lin Shouning, Huang Guihua, Wang Zhenchang Rui Kang Hospital, Guangxi College of TCM (Guangxi Nangning 530001) Graduate in 2001 Grade, Guangxi College of TCM (Guangxi Nangning 530001);The Study of ZhuangGanZhuYuJian on Serum Markers in the Rat Model of Liver Fibrosis[J];Shenzhen Journal of Integrated Traditional Chinese and Western Medicine;2004-01
4 FENG Sheng-gang,XIE Xi-sheng,DENG Yao,et al(West China Hospital of Sichuan University,Chengdu 610041,China);Panax Notoginsenosides attenuates UUO-induced renal interstitial fibrosis:effect on TGF-β/Smads signal pathway[J];Medical Journal of West China;2007-04
5 QUAN Yan, XIA Qian - ming, LI Fu - xiang, LI Hong - yan, XIAO Zhen - liang 1:Department of Respiratory Diseases, General Hospital of Chengdu Military Co mmand, Chengdu, 610083.;Effect of Panax Notoginsenosides on pulmonary fibrosis induced by bleomycin in rats[J];Medicial Journal of National Defending Forces in Southwest China;2005-03
6 QUAN Yan,XIA Qian-ming,LI Fu-xiang,LI Hong-yan,ZHANG Ding-tao Department of Respiratory Disease,General Hospital of Chengdu Military Command,Chengdu,610083,China.;Effects of panax notoginsenosides on pulmonary fibrosis and CTGF expression in rats[J];Medical Journal of National Defending Forces in Southwest China;2009-01
7 LI Wu1,SHEN Zhi-qiang2,DUAN Li-fang1,et al.(1.Department of Infectious Disease,First Affiliated Hospital of Kunming Medical University,Kunming,Yunan 650032,China;2.Key Lab-oratories of Pharmacology for Natural Products of Yunnan Provence,Kunming Medical University,Kunming,Yunnan 650032,China);Effect of Sanqidanshen Tablet on experimental liver fibrosis[J];Modern Medicine & Health;2009-07
8 FENG Xing, XU Dong-Hui, MEI Xue-Ting, ZHU Liang, XU Shi-Bo (Lab of Chinese Medicine and Marine Drugs, School of Pharma Ceutical Sciences, Zhongshan University,Guangzhou 510275);Protection of iron-induced toxicity in rat hepatocyte culture by (+)-catech in and fisetin[J];Chinese Pharmacological Bulletin;2003-12
9 XUE Qing1,XUE Shao-li2,WANG Ya-song2, ZHANG Jing3, WANG Yi2, XIA Mi-zhen2(1.Grade 2003 ,Xuanwu Hospital,Capital Medical Science University,Beijing 100053,China;2.Department of Medical Biotechnology,Anhui Medical University,Hefei 230032,China ;3.Grade 2002, Specialty of Biological Technology ,Anhui Medical University ,Hefei 230032,China);Effect of PNS on Collagen Synthesis in HSC-T6 Cells[J];Herald of Medicine;2008-05
10 WANG Chao liang 1, KE Jin hu 1, FAN Jia hong 2, CUI Xiu ming 1 (1.Wenshan Prefecture Institute of Sanqi Science and Technology Wenshan Yunan, 663000, China;2.Samson Biology Science and Technology Co., Ltd Wenshan Yunnan, 663000, China);Protection of Sanqibaogan Capsules against the acute and chemical liver injury in mice[J];Chinese Traditional Patent Medicine;2004-11
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Chai Wenshu,Yu Jingbo,Li Yongchun.Department of Respiratory Disease,The First Affiliated Hospital,Jinzhou Medical College,Jinzhou 121001;Influence on morphology and collagen of angelica sinensis on pulmonary fibrosis in rats[J];Chinese General Practice;2004-08
2 CHEN Zuo-ran,ZHANG Xiang-jian,XU Li,et al.Department of Neurology,The Second Hospital of Hebei Medical University,Shijiazhuang 050000,China;The Expression and Significance of COX-2 after Cerebral Artery Occlusion(MCAO) in Experimental Rats[J];Chinese General Practice;2006-02
3 LI Su - yun (The First Affiliated Hospital of Henan College of TCM, Zhengzhou 450000, China);Prof. CAO Shi - hong's Experience on the Treatment of Interstitial Pulmonary Fibrosis[J];New Journal of Traditional Chinese Medicine;2003-09
4 SUN Shu zhen, WANG Yi, TIAN Yong jie,et al (Dept. of Pediatrics,Shandong Provincial Hospital);A study on the changes of nitric oxide in experimental diabetic rat[J];Acta Academiae Medicinae Shandong;2002-05
5 Xin Hongtao, Song Xiujie, Xu Shaohua, Mu Xiaoyan,Wan g Jing, Jin Changjun, Huang Chen Department of Respiratory Diseases, Shandong Provincial Hospital;Therapeutic Effects of Qidan Granule and Expressions of TGF-β and TNF-α on Rats with BlemycinA_5 Induced Pulmonary Fibrosis[J];Journal of Capital University of Medical Sciences;2004-01
6 SHI Jun ying,LI Bao guo,MU Cai ping (Shandong University of Traditional Chinese Medicine,Jinan 250014,China);POLYSACCHARIDE'S CONTENT DETERMINATION OF GLEHNIA LITTORALIS[J];Journal of Shandong University of Traditional Chinese Medicine;2002-02
7 KONG Ling jun,LI Guang hua,LI Lu yang (Qilu Hosp.,Shangdong Univ.,Jinan 250012,China);CORRELATION BETWEEN SENILE BLOOD-STASIS SYNDROME AND CELL ADHESION MOLECULES[J];Journal of Shandong University of Traditional Chinese Medicine;2003-04
8 Xin Hong Tao,Zhou Xiao Hui,Liu Cheng,et al;Treatment of pulmonary fibrosis with the method of Yi Qi Huo Xue(YQHX):a report of 18 cases[J];Shandong Medical Journal;2001-24
9 CAI Hou rong 1,DAI Ling juan 1,ZHENG Pei de 1,MENG Fan qing 2(1 Department of Respiratory Disease,Gulou Hospital,Nanjing 210008;2 Department of Pathology,Gulou Hospital,Nanjing 210008);Expression of Transforming Growth Factor-β1 in Lungs of Bleomycin-induced Pulmonary Fibrosis[J];Shanghai J.of Immunology;2001-02
10 LI Hui ping,LI Xia,HE Guo jun,YI Xiang hua,CAI Ying yun △, Charlie Strange △△ (Department of Respiratory Diseases,Shanghai Pulmonary Hospital,Shanghai 200433; △Department of Pulmonology,Zhongshan Hospital,Fudan University,Shanghai 200032,China; △△ Medical University of South Carolina,SC 29425,USA);Influence of Dexamethasone on the Proliferation & Apoptosis of Pulmonary Inflammatory Cells in Bleomycin-Induced Pulmonary Fibrosis in Rats[J];Journal of Shanghai Medica(University);2004-04
China Proceedings of conference Full-text Database 1 Hits
1 ZHU Di. The First Hospital Affiliated to Hunan TCM College,Hunan,Changsha 410007,China;Progress of TCM clinic of collateral disease[A];[C];2005
【Secondary References】
Chinese Journal Full-text Database 8 Hits
1 Yang Xia,et al(The school of public health,Hebei Medical University,Shijiazhuang 050017);Meta-Analysis on the Change of TGF-β_1 in Pulmonary Fibrosis[J];Journal of Mathematical Medicine;2008-02
2 WANG Yi-fei,LI Hong-wei;Clinical observation of Xifeining and nicotinic acid in the treatment of silicosis[J];Acta Academiae Medicinae CPAF;2008-12
3 XU Jian-chun;Clinical survey on 128 cases of lung fibrosis treated by combination of Chinese and western medicine[J];China Occupational Medicine;2008-01
4 ZHANG Jian-feng,ZHANG Dan-shen.(North University in Hebei,Zhangjiankou 075146,China);Study Advancement in Pharmalcological Actions of Total saponins of Panax Notoginseseng[J];Medical Recapitulate;2007-06
5 SUN Shu-jun,XIANG Yang,HUANG Shi-lin(Department of Traditional Chinese Medicine Hemopathy,The 210 th Hospital of PLA,Dalian 116021,China);Progress in studies of mechanism of anti-fibrosis traditional Chinese drugs and effective components[J];China Journal of Chinese Materia Medica;2008-24
6 CHENG Zhi-qing1,XU Bai-hong1,DOU Li-ping2,LIU Wang1,WANG Juan1(1.Zhejiang Chinese Medical University,Hangzhou 310053,Zhejiang,China;2.Second Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310053,Zhejiang,China);Effects and Mechanisms of PNS on Myocardial Fibrosis and Expression of PDGF-B in Chronic Viral Myoearditic Mice[J];Chinese Archives of Traditional Chinese Medicine;2008-08
7 Liu Meixia,Zhang Wengao,Liu Longtao,et alGuangzhou University of Traditional Chinese Medicine (Guangzhou 510405);Effect of Toll Like Receptor 4 in Foam Cell Formation and Intervention Study with Chinese Medicine[J];Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease;2009-04
8 Liu Yong1,Li Jun1,Gao Jian2,et al(1School of Pharmacy,Anhui Medical University,Hefei 230032;2Dept of Pharmacy,The First Affiliated Hospital of Anhui Medical University,Hefei 230022);Experimental study on pulmonary fibrosis treated with total glucosides of Danggui Buxue Decoction in rats[J];Acta Universitatis Medicinalis Anhui;2009-05
China Proceedings of conference Full-text Database 1 Hits
1 CHENG Zhi-qing~1,XU Bai-hong~1,DOU Li-ping~2,et al.~1 Zhejiang Chinese Medical University,~2 Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou(310053);Effects and Mechanisms of PNS on Myocardial Fibrosis in Chronic Viral Myocarditic Mice[A];[C];2008
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 LIANG Li_Jian, HE Qiang, LU Ming_De, PENG Bao_Gang and HUANG Jie_Fu Division of Hepatobiliary Surgery, First Affiliated Hospital, Sun Yat_Sen University of Medical Sciences, Guangzhou 510080, China;The protective effects of panax notoginseng on liver ischemia-reperfusion injury in rats[J];;1997-07
2 Liu Cheng, Xia Zhiyu, Liu Ping, Xu Lieming Institute of Liver diseases, Shanghai Academy of Traditional Chinese Medicine (200032);Experimental Study Prevention of Jian Pi Li Qi Decoction on Cirrhosis and Carcinoma[J];Chinese Journal of Integrated Traditional and Western Medicine on Liver Diseases;1998-01
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