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《China Pharmaceuticals》 2004-12
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Determination of Levofloxacin Ophthalmic Gel by HPLC

Guo Yanrong,Lu Mei,Zhang Guohong (The People's Hospital of Guangxi Zhuang Autonomous Region,Nanning,Guangxi,China 530021)  
Objective:To establish a HPLC method for determination of levofloxacin ophthalmic gel.Methods:A XTerra RP18 radial compression column was used,with a mobile phase of 0.1%phosphoric acid-acetonitrile(87 ∶13).Results:The linear range of levofloxacin was 10.0~50.0 μg/mL(r=0.999 9) and the average recovery was 99.62%,RSD=0.681%.Conclusion:HPLC was simple and feasible for the determination of levofloxacin ophthalmic gel.
【CateGory Index】: R927
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