Clinical Study of Glucocorticoid Combined with Disease Modifying Antirheumatic Drug for Treating Rheumatoid Rrthritis in 54 Cases
Zhang Wan;Department of Rheumatology, Wuhan No.1 Hospital;
Objective To investigate the clinical effect of glucocorticoid combined with disease modifying antirheumatic drug( DMARD) in treating rheumatoid arthritis( RA). Methods Totally 107 RA patients admitted to our hospital were randomly divided into the control group( 53 cases) and the combined group( 54 cases). The patients in the two groups were treated with DMARD, on this basis, the combined group were treated with low dose glucocorticoid. Results The total effective rate of the combined group was 90. 74%,which was significantly higher than 69. 81% of the control group( χ~2= 7. 428,P 0. 05),the complete disappearance time of RA inflammation and the total duration of drug treatment in the combined group were significantly shorter than those in the control group( P 0. 05).The time of morning stiffness in the two groups was significantly shortened, the number of swollen joints, the number of tender joints and the disease activity score( DAS) in the two groups were significantly decreased,and the combined group was significantly better than the control group( P 0. 05). Conclusion Compared with the single use of DMARD,the effect of DMARD combined with glucocorticoid in the treatment of RA is more obvious,it can quickly control the RA inflammatory reaction,alleviate the clinical symptoms,and improve the prognosis and life quality of the patients.
【CateGory Index】： R593.22