Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《China Pharmaceuticals》 2018-18
Add to Favorite Get Latest Update

Effect of Jishiteng Huaxian Decoction Combined with Liver Disease Therapy Instrument on the Indexes of Liver Fibrosis and Liver Function in Patients with Chronic Hepatitis B

Huang Zongwen;Yuan Yong;Lu Qian;The First Affiliated Hospital of Hainan Medical University;Cadre Sanatorium of Hainan;  
Objective To observe the effect of Jishiteng Huaxian Decoction combined with liver disease therapy instrument on the indexes of liver fibrosis and liver function in patients with chronic hepatitis B. Methods Totally 96 patients with chronic hepatitis B admitted to our hospital from January 2014 to April 2017 were selected and randomly divided into the observation group( n = 51) and the control group( n = 45) according to the random stratification method. The two groups were treated with antiviral,immunomodulation,antioxidation and anti-fibrosis,on this basis,the control group was treated with liver disease therapy instrument,and the observation group was additionally treated with Jishiteng Huaxian Decoction on the basis of the control group. The course of treatment was 1 month.Results After treatment,the liver fibrosis related indexes,the levels of alanine aminotransferase( ALT) and aspartate aminotransferase( AST) in the two groups were significantly decreased,and the those in the observation group were significantly lower than those in the control group,while the levels of serum albumin( ALB) and albumin/globulin( A/G) in the two groups were significantly increased,and the those in the observation group were significantly higher than those in the control group( P 0. 05). The liver and spleen B-ultrasound showed that the improvement of liver and spleen morphology in the observation group was better than that in the control group( P 0. 05). The total effective rate and the negative conversion rates of HBV-DNA,HBs Ag and HBe Ag in the observation group were slightly better than those in the control group,but the difference was not statistically significant( P 0. 05). The curative effect in the observation group was better than that in the control group( P 0. 05). Conclusion Jishiteng Huaxian Decoction combined with liver disease therapy instrument has certain synergistic effect in the treatment of chronic hepatitis B,it can significantly improve the indexes of liver fibrosis and liver function,which can further optimize the curative effect.
【Fund】: 海南省卫生厅科学研究课题[琼卫2012PT-32]
【CateGory Index】: R512.62;R575.2
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved