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EFFECT OF LAMINARINA JAPONICA POLYSACCHOCRIDES ON SEXUAL FUNCTION OF MALE RATS AFTER IRRADIATION OF TESTIS

LUO Qiong, REN Shi-cheng, YANG Ming-liang, YAN Jun , YANG Jia-juan (Department of Nutrition and Food Hygiene, School of Public Health, Wuhan University , Wuhan 430071,China)  
Objective To observe the effects of Laminarina Japonica polysaccharides(LJP) on sexual function and reproductive function of the local radiation damaged male rats. Method Wistar rats were randomly divided into 4 groups, the normal control group, negative control group, positive control group and LJP treatment group (50 mg/kg/d) . LJP was applied to the treatment group for 10 d before local irradiation with γ ray (6.0 Gy) . Results The incubation period of penis erection and mounting was shortened; and the percentage of mounting animals, organ coefficient of foreskin gland, sperm count, and motility rate were increased in LJP experiment group. The levels of serum T, LSH, FSH,were markedly increased but E2 markedly reduced as compared to the negative control group. Conclusion LJP can increase the sexual function and reproductive function of local radiation damaged male rats.
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