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《Yunnan Journal of Traditional Chinese Medicine and Materia Medica》 2007-01
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A Pharmacodynamic Study on the Cough-and-Asthma-Relieving Effect of Alstonia

YANG Yong,ZHOU Lin,LI Ying,et al.(Kunming Medical College,Kunming,Yunnan,650031)  
Objective: To observe the cough-and-asthma-relieving effect of Deng Tai Ye and define its effective part.Methods: A citric acid spraying method was used to establish guinea pig model for the observation of the effective part of the cough-asthma-relieving effect of alstonia.A mice trache-phenol red excretory model was used to observe different effective part of phlegm-eliminating effect.A mice auricular intumesce model induced by xylene was used to observe the effective part of anti-inflammatory effect.Results: In the different composition,alkaloid had a strong cough-relieving effect,and flavorne had a strong asthma-relieving and anti-inflammatory effect while their mixture also had the same strong effect.Acute toxicity test showed alstonia-leaf was safe under pharmacologoical dose.Conclusion: Alstonia-leaf has strong effects on the treatment of cough and asthma and different compositions of alstonia-leaf have different pharmacological effects
【CateGory Index】: R285.5
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