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Study on Hypoglycemic Effect of Mirabilis jalapa on Adrenergic Model Mice

LUO Liang-sheng,QU Lei-lei,YANG Li-ying,et al(School of Pharmacy,Dali University,Dali,Yunnan 671000)  
Objective:To study the effect of the extract of Mirabilis jalapa root on the blood glucose of normal mice and diabetes mice induced by adrenaline and glucose.Methods:High blood glucose model mice were made by 160μg/kg adrenaline solution and 10% glucose solution.The hypoglycemic effect of the extract of Mirabilis jalapa root on the blood glucose of the model mice was observed.Results:The low,middle and high dose of the extract of Mirabilis jalapa root had no effect on the normal mice(P0.05),but the high dose of the extract could lower the blood glucose levels of the adrenalin and high blood glucose mice(P0.05).Conclusion:The extract of Mirabilis jalapa has a certain hypoglycemic effect on the high blood glucose model mice induced by the adrenaline and glucose.
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