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The Value of the Urine Leukocyte Esterase Test in Diagnosing the Urethritis in Male

ZHANG Hai-ping,LIAN Shi,CHA Han (Department of Dermatology,Xuanwu Hospital of the Capital University of the Medical Sciences,Beijing 100053,China)  
Objective To evaluate the use of urine leukocyte esterase test(LET) in diagnosing the infection caused by Neisseria Gonorrhoeae(NG) and Chlamydia trachomatis(CT) in male.Methods Urethral swabs for NG culture as well as First void urine(FVU) for ligase chain reaction(LCR) and LET were collected from 129 males in a STD clinic in Beijing.Results 10 subjects were positive with NG.7 cases were positive with CT.The syndromic approach had a sensitivity of 35.29% and a specificity of 97.32% for the presence of NG or CT as well as the LET had a sensitivity of 58.82% and a specificity of 95.54% in men.Conclusion Syndromic Approach is recommended to use to the men who have urine discharge in this area.The LET has a high specificity and is a useful tool to find out asymptomatic men with infection of NG/CT.
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