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The Observation of Valacyclovir Hydrochloride Suppression for Preventing Relapse of Genital Herpes

LIU En-rang,CHEN Bin,XIE Qian, et al (The Department of Dermatology,The Second People Hospital of Shenzhen City,Shenzhen 510835,China)  
Objective To investigate relapse rate of recurrent genital herpes in the stage of valacyclovir hydrochloride lizhuwei suppression therapy.Methods The patients with recurrent genital herpes were dosed lizhuwei 300 mg Bid.after herpes resolution and clinic cure,the patients continued to take lizhuwei 300 mg once a day for 4 weeks.and then,the dose of lizhuwei were decreased to 300 mg once two days for more than one year. Results 46 patients with genital herpes were observed,there is a unrelapse rate of 86.96%and 71.74% respectively in continued dosing of 3 months and one year.and also there is a unrelapse rate of 80.43%,84.78%and 82.61% respectively in the second,the third and the fourth three months of continued dosing.Conclusion Lizhuwei suppression therapy have high effect in preventing relapse of genital herpes.
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