Full-Text Search:
Home|About CNKI|User Service|中文
Add to Favorite Get Latest Update

Investigate Chronic Urticaria Patient’s Condition Correlating to C3, C4 of Peripheral Blood

HE Ze-sheng1, AN Guo-zhi2, ZHAO Hai-chun3 (1. Department of Graduate Faculty, Hebei North University, Zhangjiakou 075000, China; 2. Department of Dermatology, the First Affiliated Hospital Hebei North University, Zhangjiakou 075000, China; 3. Department of Clinical Laboratory, the First Affiliated Hospital Hebei North University, Zhangjiakou 075000, China)  
Objective To investigate the expression of C3, C4 and IgG in peripheral blood of patients with chronic urticaria(CU) and its correlationship with CU patients’ severity. Methods The expression of C3, C4 and IgG was measured by Immune Turbidimetry in 19 patients with acute urticaria(AU), 146 patients with CU and 20 normal controls. The severity of 165 patients with uricaria was evaluated by Urticaria Activity Score (UAS). Results There were no statistically difference in the expression of C3, C4 and IgG between AU and CU patients(P0.05), between male and female CU patients respectively(P0.05). The expression of IgG was higher than normal control(IgG17g/L) in 32 CU patients, and showed negative correlation with the expression of C3 and C4(P0.05). UAS was poor relation to the expression of C3, C4 and IgG in urticaria patient’s peripheral blood, but was negative correlation to the levels of C3, C4 in CU patients whose expression of IgG was higher than normal control(P0.05). Conclusion The expression of C3, C4 could respond to the severity of CU patients whose expression of IgG is higher than normal control.
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
©CNKI All Rights Reserved