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《The Chinese Journal of Dermatovenereology》 2017-05
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Analysis of Trend in Drug Resistance of Mycoplasma in Genitourinary Tract Infection in Maanshan area from 2013 to 2015

PAN Ting-meng;HU Jin-huan;WANG Xin;CHEN Xue-lu;WANG Kai-fan;TANG Di-mu;Dermatological Development of Maanshan Shiqiye Hospital;Clinical Test Center of Maanshan Municipal Hospital Group;Dermatological Development of Maanshan Municipal People's Hospital;  
Objective To reveal the trend in the drug resistance of mycoplasma in genitourinary tract infection in males and females in Maanshan in order to guide the rational use of antibiotics. Methods Ureaplasma urealyticum( UU) and mycoplasma hominis( MH) kits were used to culture specimens of 2 357 subjects from departments of dermatology,urology and gynaecology obstetrics in our hospital from 2013 to 2015. Drug resistance was also tested in the cultures. The statistical analyses were performed using the software of SPSS,version 22. 0. Results 44. 12% of specimens( 1 040/2 357) were positive for mycoplasma. Positive rates in females were higher than that in males( 56. 17% vs. 23. 41%). Mycoplasmas from over 95% of specimens were sensitive to Minocycline and Doxycycline,and 85% sensitive to Clarithromycin. Sensitivity of mycoplasmas to Quinolone antibiotics was low. Mycoplasmas were sensitive to Ofloxacin and Levofloxacin only in 20% of specimens. The sensitive rates of mycoplasmas to Josamycin,Clarithromycin,Roxithromycin,Sparfloxacin,Levofloxacin and Azithromycin were higher in males than in females( P 0. 05). The sensitive rates of mycoplasmas to Josamycin,Clarithromycin,Roxithromycin and Azithromycin trended to increase in males over recent years( P 0. 05),while in the females sensitive rates to Josamycin,Roxithromycin and Azithromycin increased annually( P 0. 05). The sensitive rates of mycoplasmas to Clarithromycin varied over the last three years. Conclusion The sensitive rates of mycoplasmas to antibiotics differ between malesand female in Maanshan. The sensitive rates of mycoplasmas to multiple antibiotics are higher in males than in females. The highest sensitive rate of mycoplasmas and stable is to Minocycline,followed by Doxycycline and Clarithromycin in males. Mycoplasmas from females exhibit stable and high sensitive rates only to Minocycline and doxycycline.
【CateGory Index】: R446.5;R691.3
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