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《The Chinese Journal of Dermatovenereology》 2017-05
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Updates in the Role of IL-33 in Autoimmunologic and Allergic Dermatoses

XIA Deng-mei;YAN Wei;LI Wei;Department of Dermatovenereology,West China Hospital of Sichuan University;  
IL-33,a member of interleukin-1 family,can induce Th2 cytokines by binding to its specific ST2 receptor and activating the downstream signaling pathway. IL-33 can not only regulate Th2-mediated immune reaction and activate mast cells to produce inflammatory cytokines,but also serve as a nuclear factor regulating gene translation. It plays a potential pathogenic role in autoimmune and allergic dermatoses.
【CateGory Index】: R758.2
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【Secondary Citations】
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1 LIU Ling-ling * ,ZHU Xue-jun,JIANG Wei,CHEN Xi-xue,LI Ming,PENG Zhen-hui,GUO Zai-pei,LI Fu-qiu.* Department of Dermatology,Peking University First Hospital,Beijing100034,China;A Multicentre,Double-blind,Randomized,Parallel Comparative Study on the Efficacy and Safety of Mizolastine versus Loratadine in the Treatment of Chronic Urticaria[J];中华皮肤科杂志;2003-06
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