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An Experiamental Study on Potassium Iodide Treaatment of Sporotrichosis.

Liu Xiaoming,Lin Xiran,Sun Yixin.Department of Dermatology,first Affiliated Hospital,Dalian Medical University.Dalian 116011  
In this study,experimental infection of Sporotrichum schenckii was produced in normal and immunosuppressed mice.The effects of potassium iodide treatment were observed in reation to the changes of the micro-organisms and the inflammatory cells of the hosts during the development of experimental lessions.The results confirmed that the therapeutic effect of potassium iodide on sporotrichosis was related to the host immuno-mechanism.Evidence indicated that the potassium iodide might promote macrophayes infiltration in the sites of infection and promote the host resistant agaist sporotrichosis.The results showed that potassium iodide was not effective in treating systemic sporotrichosis of mice.Its effect on the disseminated cutaneous form of sporotrichosis was varied according to the mouse immunologic status.
【CateGory Index】: R756
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