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《Chinese Journal of Urban and Rural Industrial Hygiene》 2009-03
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Effects of aeronautical environmental on Bone Mineral Density and Bone Metabolism marker in Aircrew Members of Civil Aviation

Peng Xin- tao1 , Chen Wei- ru2 (1.China Southern XinJing Airlines,Urumqi, 830016 2.Institute of Aviation Medicine, Civil Aviation University of China,Tianjin,300300)  
Objective To explore the effects of aeronautical environmental factors on bone metabolism and bone mineral density in aircrew members of civil aviation, we analyzed the correlations between the level of bone metabolism,bone mineral density and flight hours in aircrewmembers of civil aviation.. Methods 139 healthy male aircrewmembers of civil aviation (20~60 years) and 37 healthy male controls (20~ 60 years) were randomly selected and were divided into four different age groups (20~, 30~,40~ ,50- 60years old). Bone mineral density (BMD) was measured with single- photon bidimensional ultra- distal bone mineral density, Bone gla protein (BGP) was measured with radioimmunoassay and bone specific alkaline phosphatase(BALP) was measured with enzyme- linked immunoassay. The results were analyzed with t-test, the correlations between the variables and the flight hours were analyzed with linear correlation. Results The results showed that Standard deviation (SD)of BMD were lower in different aged aircrewmembers of civil aviation than the control group (P 0.05), the BMD of ulna was obviously lower in group aged 50- 60 than in the control group (P 0.05), the effect of flight hours on the BMD of ulna is more sensitive than on the radius, both BGP and BALP were lower in aircrew members of civil aviation compared with control group . The BGP and BALP were significantly lower in groups aged 20 ~ and 30~ than in control group respectively(p0.01), while there was no statistical difference between two groups in 40~ group(p0.05). The BGP and BALP were significantly inverse correlated with cumulative flight hours (P 0.01). Conclusion These results suggested that the aeronautical environmental factors may reduce the level of BMD in aircrewmembers of civil aviation, the ulna is more sensitive than the radius. the aeronautical environmental also influence the level of bone metabolism in aircrewmembers of civil aviation , which was correlated with their flight hours.
【CateGory Index】: R85
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