Alkaloids from Lanceleaf Thermopsis (Thermopsis lanceolata)
Gao Wenyun; Li Yiming and Zhu Dayuan (Department of Phytochemistry, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031)
Six quinolizidine-type alkaloids were isolated from the whole plant of Thermopsis lanceolata R.Br.. They were thermopsine(Ⅰ), 13β-hydroxylthermopsine(Ⅱ), cytisine(Ⅲ), N-methylcytisine(Ⅳ),5, 6-dehydrolupanine(Ⅴ) and N-(3-oxobutyl) cytisine (Ⅵ) respectively. Compound Ⅱ and Ⅴ were obtained from. this species for the first time while compound Ⅵ was isolated for the first time from genus Thermopsis. All structures were elucidated on the basis of physico-chemical contants and spectroscopic evidences.