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《Chinese Traditional and Herbal Drugs》 2006-02
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Quality evaluation of Rhizoma Coptidis in different growing years by microcalorimetry

DAI Chun-mei~(1,2),XIAO Xiao-he~1,WANG Di~2,SUN Yu-qi~2,JIN Cheng~1,FAN Dong-li~3,ZHAO Yan-ling~1,LIU Yi~4,ZHAO Xiang-jun~1(1.No.302 Hospital of PLA,Beijing 100039,China;2.Jinzhou Medical College,Jinzhou 121001,China;3.Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100094,China;4.College of Chemistry,Wuhan University,Wuhan 430072, China)  
Objective To establish a set of methods of Chinese materia medica quality evaluation based on biothermodynamics.Methods Using microcalorimetry,the thermal power of Escherichia coli meta-bolism affected by Rhizoma Coptidis in different growing years was measured.According to the thermokinetic model,the relationship of the thermokinetic parameters,caloric bioactivity and chemical constituent was analyzed.Results There were obvious difference in the caloric active fingerprints of E.coli metabolism affected by Rhizoma Coptidis in different growing years,which presented significant finger character.Compared with the normal groups,the metabolism of E.coli was inhibited in different levels by Rhizoma Coptidis in different growing periods,the multiplication rate constants and heat output were decreased,and the generation time was prolonged.Especially,Rhizoma Coptidis under four years' growing period with the highest content of total alkaloids showed a significant inhibitory effect on E.coli.Conclusion There are evident correlation among the thermokinetic parameters of E.coli metabolism affected by Rhizoma Coptidis in different growing years,the caloric bioactivity,and chemical composition.The thermokinetic parameters can indirectly reflect caloric bioactivity of Rhizoma Coptidis.As the method of biothermodynamics is on line,microamount,high throughout screening,and universality.The microcalorimetry is considered to be a useful mean for Chinese materia medica quality evaluation.
【Fund】: 国家自然科学基金资助项目(3997091130371724)
【CateGory Index】: R282
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【References】
Chinese Journal Full-text Database 10 Hits
1 HUANG Xu-Jun,LI Qiang-Guo,LIU Han-Sheng,et al(Department of Chemistry and Life Science,Xiangnan University,Chenzhou,Hunan 423000,China);Microcalorimetry Study on the Escherichia Coli Metabolism Affected by Rhubarb Roots in Different Areas[J];Journal of Xiangnan University;2006-04
2 LI Ya-jie1,QIN Da-ji1,2,YANG Yong-kang1,2,LONG Lan1,XIANG Ji-qian1,2(1.Enshi Qingjiang Bio-Engineering Co.,Ltd.,Enshi 445000,China;2.West Comprehensive Experiment Station of Hubei Provincial Agriculture S&T Innovation Center,Enshi 445000,China);Current Quality Evaluation of Authentic Medicinal Material[J];Journal of Hubei University for Nationalities(Natural Science Edition);2010-04
3 LI Zhao-yi,HUANG Zhen 1 2 School of Pharmacy,Zhejiang University of TCM,Hangzhou 510053,China;Research Advances on Quality Control Techniques and Evaluation of Rhizoma Coptidis[J];Anti-Infection Pharmacy;2010-03
4 Wang Jiabo,Li Huifang,Xiao Xiaohe,Jin Cheng (PLA Institute of Materia Medica, 302 Hospital of PLA, Beijing 100039);Bioassay Based TCM Quality Control[J];World Science and Technology-Modernization of Traditional Chinese Medicine and Materia Medica;2007-06
5 Zhang Yi, Fan Gang, Geng Zhipeng, Tong Yingpeng, Liu Jilin (College of Ethnic Medicine, Chengdu University of TCM, Chengdu 611137, China);On the Research Design of Integrated Investigation Idea of Quality Evaluation for Famous-region Drug[J];World Science and Technology(Modernization of Traditional Chinese Medicine and Materia Medica);2009-05
6 LIU Lian, LIN Gui-mei, SHAO Wei(School of Pharmaceutical Science Shandong University, Jinan 250012, China);Application of Microcalorimetry in the Research of Microorganism and Cell[J];Pharmaceutical Biotechnology;2010-01
7 ZHANG Qian1,2,JIN Cheng1,XIAO Xiao-he1,WU Yan-shu1,2,YAN Dan1,YIN Rong-li2(1.302 Hospital of PLA and PLA Institute of Chinese Materia Medica,Beijing 100039,China;2.College of Pharmacy,Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China);Probe of early prediction methods for adverse drug reaction and quality fluctuation in Chinese materia medica injection[J];Chinese Traditional and Herbal Drugs;2009-03
8 ZHONG Ling-yun,SUN Ying-ying,GONG Qian-feng(Pharmaceutical College,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China);Research status and prospect of processing effect on property of Rhizoma Coptidis[J];Chinese Traditional and Herbal Drugs;2010-02
9 DAI Chun-mei1,2,3,PENG Cheng3,WANG Jia-bo2,XIAO Xiao-he2(1.Liaoning Medical University,Jinzhou 121001,China;2.Institute of Chinese Materia Medica,302 Hospital of People′s Liberation Army,Beijing 100039,China;3.College of Pharmacy,Chengdu University of Traditional Chinese Medicine,Chengdu 610000,China);Dose-effect relationship of berberine and analogues on antibacterial metabolism of Bacillus shigae by microcalorimetry[J];Chinese Traditional and Herbal Drugs;2010-07
10 CAO Jun-ling, LI Zu-lun, XIAO Xiao-he, et al Pharmacy Department, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing (100700);Effects of 3 Genosides on Bio-thermodynamic Expression of Splenic Lymphocyte in Mice[J];Chinese Journal of Integrated Traditional and Western Medicine;2008-01
China Proceedings of conference Full-text Database 1 Hits
1 Cao Juning,Li Zulun,Xiao Xiaohe 1 Pharmacy Department,Dongzhimen Hospital Affiliate to Beijing University of TCM(Beijing 100700);2 PLA Institute of Chinese Material Medica,302 Hospital of PLA(Beijing 100039);3 College of Pharmacy,Chengdu University of TCM(Sichuan 610071);Effects of Biothermo-activity of 3 Genosides on Escherichia coli[A];[C];2008
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Zhao Zhiping Shen Yeshou Ge Shengfang Hu Jianju (Department of Biology Anhui University Hefei 230039);Study on Isolation and Hypoglycemic Activity of Polysaccharide of Mudan Cortex (PSM) of Paeonia Suffruticosa andr[J];JOURNAL OF ANHUI UNIVERSITY(NATURAL SCIENCES);1999-02
2 YANG Jun-bao et al (School of Life Science, China West Normal University, Nanchong, Sichuan 637002);Research Advances of Coptis[J];Journal of Anhui Agricultural Sciences;2005-07
3 MIAO Ya-mei et al(Yanjiang Institute of Agricultural Sciences of Jiangsu,Rugao,Jiangsu 226541);Gray Correlation Analysis between the Agronomic Trait and the Yield of Fresh Soybean Pod[J];Journal of Anhui Agricultural Sciences;2008-36
4 Zhang Buchang et al (Biology Dept,Anhui University,Hefei, 230039 );Study on extraction, purification and blood - sugar lowering of a polysaccharide from danpi (root shin of Paeonia suffruticasa Andr. )[J];JOURNAL OF ANHUI AGRICULTURAL SCIENCES;1995-04
5 LIU Wei~1,ZHOU Jian-li~2,ZHOU Shu-juan~2,BAN Yong-shen~3(1.Taihe County Institute for Drug Control,Taihe,Anhui 236600;2.Anhui College of TraditionalChinese Medicine,Hefei 230038;3.Jiangxi College of Traditional Chinese Medicine,Nanchang 330006);The fluorescent observation of common traditional Chinese medicine[J];Anhui Medical and Pharmaceutical Journal;2006-05
6 FU Zhi jun, LIN Yi ning, KANG Jun瞱ei(China Pharmaceutical University, Jiangsu Nanjing 210009,China);Influence of Processes of Concentration,Refine and Dryness onSoluble Constituent of Extractive Solution of Compound Saliva Miltiorrhiza[J];Journal of Anhui Traditional Chinese Medical College;2003-02
7 Zou Guolin; Li Hai(School of Life Science,Wuhan University,Wuhan 430072 ,China);The Application of the Microcalorimetric Method to Life Science[J];AMINO ACIDS & BIOTIC RESOURCES;1996-02
8 Wang Miqu,Yan Shilin,Li Weihong,et al Chengdu University of TCM,Chengdu(610075);A Study on Chinese Herb of Cold and Hot on SD Rats[J];Journal of Zhejiang College of Tcm;2002-06
9 Wang Chunyan, Wang Peng, Wang Zhenguo Shandong University of TCM, Ji’nan(250014);Origin and Development of Chinese Medicine Four-nature Theory[J];Journal of Zhejiang University of Traditional Chinese Medicine;2009-01
10 FU Cheng-Jie ①② YU Ting ①② MIAO Wei ① SHEN Yun-Fen①(① Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072;② Graduate School of the Chinese Academy of Sciences, Wuhan Branch 430072, China);Tetrahymena:a Good Model Organism for Toxicology and Ecotoxicology[J];Chinese Journal of Zoology;2005-01
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 JIN Jian-ling,HUA Guo-qiang,MENG Zhen,GAO Pei-ji State Key Laboratory of Microbial Technology,School of Life Sciences,Shandong University,Jinan 250100,China;Antibacterial Mechanisms of Berberine and Reasons for Little Resistance of Bacteria[J];中草药(英文版);2011-01
2 ZHENG Lu-lu1,YANG Yan-hong2,ZHANG Gui-jun1 1.School of Chinese Materia Medica,Beijing University of Traditional Chinese Medicine,Beijing 100102,China 2.Tianjin Institute of Pharmaceutical Research Pharmaceutical Responsible Co.,Ltd.,Tianjin 300193,China;Discussion on reasonable application of Chinese materia medica in clinic[J];Drugs & Clinic;2011-04
3 Wu Wei1,Zhang Chun-ji2,Miao Ming-san1 Henan College of Chinese Medicine,Zhengzhou,Henan,China 450008 Science and Technology Bureau of Zhengzhou City,Zhengzhou,Henan,China 450000;Study on Genuine Traditional Chinese Assessment Mode[J];China Journal of Chinese Medicine;2011-03
4 TAO Yan-rong 1,CHEN Xi2(1.Dong ZhiMen Hospital of Peking TCM University,Beijing 100101,China;2.Institute of Medicinal Plant Development,Chinese Academy of Medical Science and Peking Union Medical College,Beijing 100193,China);Current status of Traditional Chinese Medicine(TCM)quality evaluation methods at home and abroad[J];Pharmacy and Clinics of Chinese Materia Medica;2011-02
5 Luo Yun1,2, Yan Dan1, Jin Cheng1, Wang Qiang3, Liu Youping2, Xiao Xiaohe1 (1. PLA Institute of Chinese Materia Medica, Beijing 100039, China; 2. College of Pharmacy, Chengdu University of TCM, Chengdu 611730, China; 3. Department of Pharmacy, Navy General Hospital, Beijing 100037, China);Early Detection of Changed TCM Preparation Quality: Antibacterial Effects of Radix Isatidis Water Extracts Prepared Using Different Drying Methods in the Context of Biothermodynamics[J];World Science and Technology(Modernization of Traditional Chinese Medicine and Materia Medica);2009-03
6 Nong Wei-liang,Guan Xiao,Xu Fei(School of Medical Instrument and Food Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China);Study on Rapid Detection Method of the Microbial Biomass in Food by Microcalorimetry[J];Food and Fermentation Industries;2010-11
7 Wang Haifeng,Guo Bing,Xu Li,et al.;Effects of Ginsenosides on CD4~+/CD8~+ T cell ratio and concentration of TNF-α in immunosuppressive mice[J];China Feed;2011-14
8 LI Chun-yu1,2,XIANG Zong-shang1,SONG Zi-hui1,CAI Yong-ming1,ZHANG Zong-peng1 1.Tianjin Center for Drug Safety Evaluation and Research,Tianjin Institute of Pharmaceutical Research,Tianjin 300193,China 2.Chengdu Universty of Traditional Chinese Medicine,Chengdu 611137,China;Adverse reaction of Chinese materia medica[J];Drug Evaluation Research;2011-01
9 LIU Lian, LIN Gui-mei, SHAO Wei(School of Pharmaceutical Science Shandong University, Jinan 250012, China);Application of Microcalorimetry in the Research of Microorganism and Cell[J];Pharmaceutical Biotechnology;2010-01
10 KONG Wei-jun 1,2,ZHAO Yan-ling 1,SHAN Li-mei1,XIAO Xiao-he1,GUO Wei-ying2,LIU Jun1(1.PLA Institute of Chinese Materia Medica,302 Hospital of PLA,Beijing 100039,China;2.Pharmacy College,Liaoning medical university,Liaoning Jinzhou 121001,China);Biothermo-kinetic study on the drug property differences of Zuojin Pill and its similar prescriptions[J];Chinese Traditional Patent Medicine;2008-12
China Proceedings of conference Full-text Database 2 Hits
1 Cao Juning,Li Zulun,Xiao Xiaohe 1 Pharmacy Department,Dongzhimen Hospital Affiliate to Beijing University of TCM(Beijing 100700);2 PLA Institute of Chinese Material Medica,302 Hospital of PLA(Beijing 100039);3 College of Pharmacy,Chengdu University of TCM(Sichuan 610071);Effects of Biothermo-activity of 3 Genosides on Escherichia coli[A];[C];2008
2 Xiao Xiao-he,Yan Dan,Yuan Hai-long Wang Jia-bo (China Military Institute of Chinese Materia Medica,302 Military Hospital of China, Beijing 100039);The novel patterns of efficient constituent recognition and quality control for Chinese medicines based on component knock-out & knock-in[A];[C];2009
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