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《Chinese Traditional and Herbal Drugs》 2009-01
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Technical condition for semi-bionic extraction of Vernonia anthelmintica by uniform design

LIU Xiao-dong1,YAN Ming2,GAO Li-li3,HUO Shi-xia1,ZHANG Lan-lan1(1.College of Pharmacy,Shihezi University,Shihezi 832003,China;2.Xinjiang Institute of Traditional Uighur Medicine,Urumqi 830049,China;3.Graduate School,Yangtze University,Jingzhou 434023,China.)  
Objective To optimize the best condition of semi-bionic extraction for Vernonia anthelmintica.Methods The best condition of the semi-bionic extraction for V.anthelmintica by uniform design was optimized with total HPLC integrate area of common peaks in fingerprints,total flavonoids and dried extract weight as the indexes.Results According to industry production condition,the best technical condition:pH values of 80% ethanol for the 1st,2nd,and 3rd decoctions were in order of 6.0,6.5,and 8.0,and the extraction time were 1,0.5,and 0.5 h,respectively.Conclusion It is better for V.anthelmintica extracted by semi-bionic extraction,and the parametrs are optimized by uniform design.
【Fund】: 国家科技支撑计划项目(2007BAI30B00;2007BAI48B06)
【CateGory Index】: R284.2
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