Two new flavonoid glycosides isolated from seed residue of Hippophae rhamnoides ssp. sinensis
GAO Wen1,ZHANG Jing1,2,CHEN Chao1,KONG De-yun1 1.State Key Laboratory of New Drug & Pharmaceutical Process,Shanghai Institute of Pharmaceutical Industry,Shanghai 200040,China 2.Shandong Lukang Pharmaceutical Co.,Ltd.,Jining 272100,China
Objective To study the chemical constituents in the seed residue of Hippophae rhamnoides ssp. sinensis.Methods Various chromatographic methods were employed to isolate the compounds and their structures were established by detailed spectroscopic analysis.Results Three compounds were isolated from 70% ethanol extract from the seed residue of H.rhamnosides ssp. sinensis and identified as kaempferol-3-O-[(2E)-2,6-dimethyl-6-hydroxy-2,7-octadienoyl-(1→6)]-β-D-glucopyranosyl-(1→2)-β-Dglucopyranoside-7-O-[(2E)-2,6-dimethyl-6-hydroxy-2,7-octadienoyl-(1→3)]-α-L-rhamnopyranoside(1),kaempferol-3-O-[(2E)-2,6dimethyl-6-hydroxy-2,7-octadienoyl-(1→6)]-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside-7-O-[(2E)-2,6-dimethyl-6-hydroxy-2,7octadienoyl-(1→2)]-α-L-rhamnopyranoside(2),and isorhamnetin-3-O-β-D-rutinoside(3).Conclusion Compounds 1 and 2 are new flavonoid glycosides,named seabuckthorn flavonoid glycoside A and seabuckthorn flavonoid glycoside B,respectively.
【CateGory Index】： R284.1