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《Chinese Traditional and Herbal Drugs》 2013-15
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Chemical constituents in fruits of Forsythia suspensa

WU Yan-fang1,WANG Xin-sheng2,YUAN Yong-liang1,BAI Su-ping1,ZHENG Jian-fang3 1.Pharmaceutical College,Xinxiang Medical University,Xinxiang 453003,China 2.Chemical Engineering and Pharmaceutical College,Henan University of Science and Technology,Luoyang 471003,China 3.Sanquan College,Xinxiang Medical University,Xinxiang 453003,China  
Objective To study the chemical constituents from the fruits of Forsythia suspensa.Methods Compounds were isolated and purified by silica gel chromatography,repeated recrystallization,and other methods,and their structures were identified by spectral analysis.Results Eleven compounds were isolated from the fruits of F.suspensa and were identified as acetyloleanolic acid(1),isobauerenyl acetate(2),β-amyrin acetate(3),cleroindicin A(4),1-methyl-β-D-glucopyranoside(5),esculentic acid(6),asiatic acid(7),forsythin(8),oleanolic acid(9),β-sitosterol(10),and β-daucosterol(11).Conclusion Compounds 1 and 4-7 are obtained from the plant of Forsythia Vahl for the first time.
【Fund】: 国家自然科学基金资助项目(81072552);; 河南省科技创新杰出青年基金项目(104100510016);; 新乡医学院省级重点学科开放课题(ZD200968)
【CateGory Index】: R284.1
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