Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Traditional and Herbal Drugs》 2013-15
Add to Favorite Get Latest Update

Preparation and anti-oxidative activity of hydroxytyrosol by alkaline hydrolysis of oleuropein

XIE Pu-jun 1,2,HUANG Li-xin 1,2,ZHANG Cai-hong 1,2,YOU Feng 1,2,ZHANG Yao-lei 1,2 1.Key Laboratory of Biomass Energy and Material,Jiangsu Province,Key and Open Laboratory on Forest Chemical Engineering,SFA,National Engineering Laboratory for Biomass Chemical Utilization,Institute of Chemical Industry of Forest Products,Chinese Academy of Forestry,Nanjing 210042,China 2.Institute of New Technology of Forestry,Chinese Academy of Forestry,Beijing 100091,China  
Objective To prepare hydroxytyrosol(HT) by alkaline hydrolysis of oleuropein and to investigate its anti-oxidative property.Methods According to single factor experiments,four variables: temperature,sodium hydroxide concentration,time,and the ratio of solid to liquid,were selected.On the basis of single factor experiments,orthogonal tests of L9(34) were carried out.HPLC-MS method was also further applied for the qualitative analysis on HT.Under the same conditions,contrast experiments on the acid and alkaline actions were made.Finally,anti-oxidative activity of HT was evaluated.Results The results showed that the selected variables were all highly significant.Also,the descending influence orders on HT were temperature sodium hydroxide concentration time the ratio of solid to liquid.Lastly,the optimal conditions on HT yield were obtained as follow: temperature 90 ℃,sodium hydroxide concentration 0.2 mol/L,time 45min,and the ratio of solid to liquid 1∶15.The HPLC retention time of HT was about 10.3 min,and its relative molecular weight of fragment ion by MS was 134.8.By comparison with the acid action,it was proved that the alkaline action was better in HT yield.In addition,the anti-oxidative activity of HT was carried out on scavenging DPPH radical.The results showed that DPPH scavenging capability of HT was 2.45 times of BHT.Conclusion HT yield is well obtained under the alkaline condition and has a good anti-oxidation.
【Fund】: “十二五”国家科技支撑计划(2012BAD32B10);; “863”课题项目“食品高效节能干燥装备开发与新技术研究”(2011AA100802)
【CateGory Index】: R284.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 5 Hits
1 XU Chao,GAO Jun-chao,ZHANG Jian,JIANG Shen-de(School of Pharmaceutical Science and Technology,Tianjin University,Tianjin 300072,China);Process Research of Hydroxytyrosol Synthesis[J];Fine Chemicals;2010-12
2 YE Jian-zhong1,2,WANG Cheng-zhang1,2,CHEN Hong-xia1,DONG Yan-he1(1.Institute of Chemical Industry of Forest Products,Chinese Academy of Forestry;National Engineering Laboratory for Biomass Chemical Utilization;Key and Open Lab.on Forest Chemical Engineering,SFA,Nanjing 210042,China;2.Institute of New Technology of Forestry,CAF,Beijing 100091,China);Content Determination and Extraction Technology of Hydroxytyrosol from Olive Leaves[J];Chemistry and Industry of Forest Products;2011-01
3 Huang Agen Dong Ruijian Lu Maolin Wang Zhijun(Yangzhou University,Yangzhou 225001,China);Separation and Purification of Polyphenols Crude Extracts from Tea Flower (Camellia sinensis L O Kuntze) and Their Antioxidative Activities[J];Transactions of the Chinese Society for Agricultural Machinery;2008-12
4 BU Wen-wen,LIU Chang-jin,TIAN Shi-fu (School of Food Engineering and Biotechnology,Tianjin University of Science and Technology,Tianjin 300457,China);Comparison of extraction of olive leaves to prepare hydroxytyrosol by hydrochloric acid and β-glycosidase[J];Science and Technology of Food Industry;2011-07
5 WANG Xiao-fei 1,2,LI Chen 1,3,ZHENG Yuan-yuan1,DI Duo-long 1 1.Key Laboratory of Chemistry of Northwestern Plant Resources & Key Laboratory for Natural Medicine of Gansu Province,Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences,Lanzhou 730000,China 2.Second Hospital of Lanzhou University,Lanzhou 730030,China 3.Instrumental Analysis & Research Center,School of Applied Physics & Material Engineering,Wuyi University,Jiangmen 529020,China;Polyphenols from leaves of Olea europaea[J];Chinese Traditional and Herbal Drugs;2011-05
Chinese Journal Full-text Database 10 Hits
1 WU Long-huo,ZHANG Jian(Pharmacy College of Gannan Medical University,Ganzhou,Jiangxi,341000);Synthesis of natural flavone:5-methoxy-luteolin[J];Journal of Gannan Medical University;2012-04
2 CHEN Bi-qiong1,NIE Yong-fei2,TU Hua1(1 College of Basic Medical Sciences,Luzhou Medical College,Sichuan Luzhou 646000; 2 College of Continuing Education,Luzhou Medical College,Sichuan Luzhou 646000,China);Research Progress on Chemical Constituents and Pharmacological Effects of Fructus Canarii[J];Guangzhou Chemical Industry;2012-21
3 GUO Qing-qi1; ZHANG Na2; LI Meng-yun1; ZHANG Zhi1; WANG Zhen-yu1,3. 1 College of Forestry, Northeast Forestry University, Harbin, 150040, P.R. China; 2 Key Laboratory of Food Science and Engineering of Heilongjiang Province, Harbin University of Commerce, 150076, P.R. China; 3 College of Food Science and Engineering, Harbin Institute of Technology, 150086, P.R. China;Relationship between polyphenols and antioxidation in larch pine cones and altitude[J];Journal of Beijing Forestry University;2013-01
4 CUI Xiao-ming1,YU Yun-chun1,ZHANG Guang-cheng2,GE Heng2 (1.Guizhou Tea Research Institute,Guiyang,Guizhou 550006;2.Xinyang City Shihe District Tea Department,Xinyang,Henan464000);Review on the Chemical Composition and Utilization of Tea [Camellia sinensis(L.)O.Kuntze] Flower[J];Heilongjiang Agricultural Sciences;2012-01
5 Han Lin Zhang Haide Li Guosheng Lu Shenghui Sheng Lingzhi (College of Food Science,Hainan University,Haikou 570228,China);Optimization of Extraction Technology and Antioxidant Activities of Total Phenol from Betel Nut Seed[J];Transactions of the Chinese Society for Agricultural Machinery;2010-04
6 YAN Yong,GUO Yuan,PENG Meng-jiao,AN Jing,EN Da(Key Laboratory of Synthetic and Natural Functional Molecule Chemistry,Ministry of Education,College of Chemistry and Materials Science,Northwest University,Xi′an 710069,Shaanxi,China);Synthesis of Hydroxytyrosol[J];Fine Chemicals;2012-10
7 WANG Cheng-zhang1,2,CHEN Qiang1,2,LUO Jian-jun3,BAI Xiao-yong4,WANG Yan1,KONG Ling-xi1(1.Institute of Chemical Industry of Forest Products,CAF;National Engineering Lab.for Biomass Chemical Utilization; Key and Open Lab.of Forest Chemical Engineerign,SFA;Key Lab.of Biomass Energy and Material,Jiangsu Province,Nanjing 210042,China;2.Institute of New Technology of Forestry,CAF,Beijing 100091,China; 3.Tourism Administration of Longnan City,Longnan 746000,China;4.Longnan Gardon City Olive Technology Development Co.,Ltd.,Longnan 746000,China);Development and Industrial Prospect of China′s Olive[J];Biomass Chemical Engineering;2013-02
8 WANG You-bing,YAN Yi,ZHOU Qing-hong(Haikou Forest Farm,Kunming 650114,China);Research Progress of Olea europaea[J];Forest Inventory and Planning;2013-01
9 BU Wen-wen,LIU Chang-jin,TIAN Shi-fu (School of Food Engineering and Biotechnology,Tianjin University of Science and Technology,Tianjin 300457,China);Comparison of extraction of olive leaves to prepare hydroxytyrosol by hydrochloric acid and β-glycosidase[J];Science and Technology of Food Industry;2011-07
10 LU Wen-jing,NING Jing-ming*,FANG Shi-hui*,JIANG Shan,WEI Huan(Key Lab of Tea Biochemistry &Biotechnology,Ministry of Education and Ministry of Agriculture, Anhui Agricultural University,Hefei 230036,China);Study on comprehensive extraction of tea polyphenol and tea saponin from tea flowers[J];Science and Technology of Food Industry;2012-11
China Proceedings of conference Full-text Database 2 Hits
1 YU Lijun,XU Jinhua,XIAO Wenjun,TIAN Na,CHEN Ling (Key Lab of Tea Science of Ministry of Education,College of Horticulture and Gardening,Hunan Agricultural University,Changsha 410128,China);Comprehensive Exploitation of Tea Polyphenol Additive to Health Protection Cigarette[A];[C];2010
2 GUAN Xingli, LUO Liyong, ZENG Liang 〔Food Science College,Southwest University,Chongqing 400715〕;Advances at the Research on the Development and Utilization of Tea Flowers[A];[C];2009
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 HUANG Hong-xia, LIN Yuan-bin(1. Department of Material and Chemical Engineering,Guilin University of Technology,Guilin 541004, China;2.College of Chemistry, Xiangtan University, Xiangtan 411105,China);Novel Method for Synthesis of 3,4-Methylenedioxy Phenethylamine[J];Fine and Specialty Chemicals;2007-12
2 HE Zhi-yong, XIA Wen-shui(School of Food Science and Technology,Southern Yangtze University, Wuxi 214036, China);Study on Extraction of Polyphenols from Canarium album (Lour.) Rauesch[J];Chemistry and Industry of Forest Products;2007-01
3 Huang Agen,Dong Ruijian,Xie Kaizhou(College of Food Science and Technology,Yangzhou University,Yangzhou 225001,China);Purification technology of polyphenols from tea flower with macroporous absorbent resin[J];Transactions of the Chinese Society of Agricultural Engineering;2007-09
4 LU Yi1 ZHANG Tong2 TAO Jian-sheng1 1. Shanghai University of Traditional Chinese Medicine 2. Experiment Center for Teaching,Shanghai University of Traditional Chinese Medicine;Study on Processing of Hydrolyzing Geniposide with β-glucosidase[J];Acta Universitatis Traditionis Medicalis Sinensis Pharmacologiaeque Shanghai;2008-03
5 Huang Agen Dong Ruijian Ge Qingfeng (College of Food Science and Technology,Yangzhou University,Yangzhou 225001,China);Studies on the Purification of Polyphenols from Tea Plant Flower by Ultra-filtration[J];Food and Fermentation Industries;2007-08
6 DONG Rui-jian HUANG A-gen LIANG Wen-juan(College of Food Science and Technology, Yangzhou University,Yangzhou,Jiangsu 225001,China);Studies on extraction process of polyphenols from tea plant flower[J];Food & Machinery;2007-01
7 NIE Shao-ping,XIE Ming-yong*,LUO Zhen(Key Laboratory of Food Science of Ministry of Education, Nanchang University, Nanchang 330047, China);Antioxidative Activity Evaluation Study on Tea Polysaccharide by Scavenging DPPH[J];Food Science;2006-03
8 HUANG A-gen,DONG Rui-jian,WEI Hong (College of Food Science and Technology, Yangzhou University, Yangzhou 225001,China);Identification and Analysis of Major Bioactive Compounds in Tea Flower[J];Food Science;2007-07
9 WU Yi1,WANG Hong-xin1,2,*,ZHU Song1 (1.State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China;2. School of Food Science and Technology, Shihezi University, Shihezi 832003, China);Comparison on Hydrolysis of Extract of Ginkgo biloba L. Leaves to Prepare Flavone Aglycone by Hydrochloric Acid and β-Glycosidase[J];Food Science;2008-07
10 JI Teng-fei,FENG Xiao-zhang  (Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical college,Beijing 100050,China);SURVEY OF CHEMICAL CONSTITUENTS AND PHARMACOLOGICAL ACTIVITIES OF OLEA L. PLANTS[J];Natural Product Research and Development;2004-04
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved