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《Chinese Traditional and Herbal Drugs》 2015-01
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Q-TRAP-LC-MS/MS analysis on nucleosides in Pseudostellariae Radix with different processing methods

MA Yang;HOU Ya;ZOU Li-si;LIU Xun-hong;XU Li;LAN Cai-wu;Nanjing University of Chinese Medicine;Yangzhou Institute for Drug Control;Guizhou Chang Hao Chinese Medicine Co., Ltd.;  
Objective To investigate the influence of different processing methods on the contents of nucleosides in Pseudostellariae Radix(PR). Methods Q-TRAP-LC-MS/MS method was applied for the analysis on 13 kinds of nucleosides in PR with different processing methods. Results The contents of cytidine, uridine, inosine, guanosine, and thymidine were higher in PR. The different processing methods of PR had certain influence on the contents of nucleosides. The amount of nucleosides in PR by oven drying was higher than that by drying in the sun. Conclusion The paper investigates the influence of processing methods on chemical composition in PR, and provides the basis for establishing reasonable processing technology.
【Fund】: 国家自然科学基金资助项目(81274016;81473312);; 国家科技支撑计划项目(2011BAI13B04);; 江苏高校优势学科建设工程资助项目(ysxk-2014)
【CateGory Index】: R284.1
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