Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《浙江大学学报(英文版)》 2005-01
Add to Favorite Get Latest Update

Predictive performance of'Diprifusor'TCI system in patients during upper abdominal surgery under propofol/fentanyl anesthesia

LI Yu-hong~1 XU Jian-hong~1 YANG Jian-jun TIAN Jie XU Jian-guo~1Department of Anesthesiology.First Affiliated Hospital,School of Medicine,Zhejiang University.Hangzhou 310003,China~2Department of Anesthesiology.Nanjing Jinling Hospital.Nanjing 210002 China  
Objective:To evaluate the predictive performance of‘Diprifusor’TCI(target-controlled infusion)system for its betterapplication in clinical anesthesia.Methods:The predictive performance of a‘Diprifusor’TCI system was investigated in 27Chinese patients(16 males and 11 females)during upper abdominal surgery under total intravenous anesthesia(TIVA)withpropofol/fentanyl.Measnred arterial propofol concentrations were compared with the values predicted by the TCI infusion system.Performance was determined by the median performance error(MDPE),the median absolute performance error(MDAPE),thedivergence(the percentage change of the absolute PE with time),and the wobble(the median absolute deviation of each PE fromthe MDPE).Results:The median(range)values of 14.9%(-21.6%~42.9%)for MDPE,23.3%(6.9%~62.5%)for MDAPE,-1.9%h~(-1)(-32.7%~23.0% h~(-1))for divergence,and 18.9%(4.2%~59.6%)for wobble were obtained from 227 samples from all patients.For the studied population,the PE did not increase with time but with increasing target propofol concentration,particularly fol-lowing induction.Conclusions:The control of depth of anaesthesia was good in all patients undergoing upper abdominal surgicaloperation and the predictive performance of the‘Diprifusor’target controlled mthsion system was considered acceptable forclinical purposes.But the relatively bigger wobble showed that the pharmacokinetic model is not so suitable and requires im-provement.
【Fund】: ProjectsupportedbyStartupFoundationforIntroducingTalentofZhejiangUniversity China
【CateGory Index】: R614
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 1 Hits
1 SHEN Bei,LIU Li,ZHU Jianfei,GU Weiling,CAO Guizhen(Department of Anesthesiology,People's Hospital of Tongzhou District,Nantong,Jiangsu Province,Nantong 226300);Clinical application of target-controlled infusion with propofol and remifentanil for elderly patients with pulmonary disease in fiberbronchoscopy[J];南通大学学报(医学版);2012-06
【Citations】
Chinese Journal Full-text Database 1 Hits
1 LI Yu-Hong, RUI Jian-Zhong~1, ZHOU Yong-Gang~2, WANG Li-Qin~3, FU Su-E~3,YANG Jian-Jun~3, LIU Fu-Kun~4, HU Shu-Ya~2, WEN Quan~5, XU Jian-Guo~(3,6) The School of Life Science, Nanjing University, Nanjing 210093; 1~Department of Clinical Pharmacology, 3~Department of Anesthesiology,4~Department of Surgery, Jinling Hospital, Nanjing 210002; 2~Deparment of Clinical Pharmacology, the 81st Hospital of PLA, Nanjing 210002, China;Population pharmacokinetics of propofol in Chinese patients[J];Acta Pharmacologica Sinica;2003-06
【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 LI Li;LI Pei;YU Chanjuan;LIU Yahua;YANG Jin;College of Pharmacy, Xinjiang Medical University;Department of Anesthesiology, the Third Affiliated Hospital of Xinjiang Medical University;China Pharmaceutical University;;Determination and analysis of Propofol in anesthesia patients' plasma of multiple nations[J];中国医药导报;2014-34
2 YANG Li-li,WANG Tian-long.Department of Anesthesiology,Xuanwu Hospital of Capital Medical University,Beijing 100038,China;Comparison of different propofol demands between epileptic and non-epileptic patients[J];中华神经医学杂志;2013-03
3 YANG Li-li,WANG Tian-long,TIAN Zhao-long.Department of Anesthesiology,Xuanwu Hospital, Capital Medical University,Beijing 100053,China;The application of propofol target-controlled infusion during electrocorticography monitoring in epilepsy surgery[J];中国医药;2012-09
4 YE Hong-bo1,ZHENG Hong2,ZHANG Xing-an3,CHI Xin-jin4,CHEN Wen-ying5,XU Jian-guo6,LI Jin-heng1,RUI Jian-zhong1*(1.Department of Pharmacology,General Hospital of Nanjing Military Command,Nanjing 210002,China;2.Department of Anesthesiology,First Affiliated Hospital of Xinjiang Medical University,Urlumgi 830054,China;3.Department of Anesthesiology,General Hospital of Guangzhou Military Command,Guangzhou 510010,China;4.Department of Anesthesiology,the Third Affiliated Hospital,SUN-Yat-Sen University,Guangzhou 510630,China;5.Department of Pharmacy,the First Affiliated Hospital of Guangzhou Medical College,Guangzhou 510120,China;6.Department of Anesthesiology,General Hospital of Nanjing Military Command,Nanjing 210002,China);Population pharmacokinetic modeling and evaluation of propofol from multiple centers[J];药学学报;2010-12
5 LI Yu-hong~1 XU Jian-hong~1 YANG Jian-jun TIAN Jie XU Jian-guo~1Department of Anesthesiology.First Affiliated Hospital,School of Medicine,Zhejiang University.Hangzhou 310003,China~2Department of Anesthesiology.Nanjing Jinling Hospital.Nanjing 210002 China;Predictive performance of'Diprifusor'TCI system in patients during upper abdominal surgery under propofol/fentanyl anesthesia[J];Journal of Zhejiang University Science;2005-01
【Co-references】
Chinese Journal Full-text Database 3 Hits
1 CHEN Wei, LI Wei, XIA Qing, WANG Jian.Department of Anesthesiology, The Center Hospital of Mianyang, Mianyang 621000, China;Application of controlled ventilation with laryngeal mask airway and T-seal adapter in fiberoptic bronchoscopy[J];实用医学杂志;2010-11
2 LI Yu-hong~1 XU Jian-hong~1 YANG Jian-jun TIAN Jie XU Jian-guo~1Department of Anesthesiology.First Affiliated Hospital,School of Medicine,Zhejiang University.Hangzhou 310003,China~2Department of Anesthesiology.Nanjing Jinling Hospital.Nanjing 210002 China;Predictive performance of'Diprifusor'TCI system in patients during upper abdominal surgery under propofol/fentanyl anesthesia[J];Journal of Zhejiang University Science;2005-01
3 CENG Zhi-yu, XU Xing, WU Xin-min. Department of Anesthesiology, First Hospital, Peking University , Beijing 100034, China;The dose-response relationship of remifentanil and propofol given by TCI for induction of anesthesia[J];中华麻醉学杂志;2004-04
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 LI Jian-qiao;WEI Fu-sheng;ZHOU Chao-jing;Department of Anesthesiology, The Central Hospital of Mianyang;;Remifentanil and protocol target controlled infusion in elderly lung disease bronchoscope application[J];中国医学装备;2015-06
2 JIANG Xun;ZHONG Shenghong;Department of Anesthesiology,the First People's Hospital of Jiujiang City in Jiangxi Province;;Comparison in two anesthetic efficacies of recumbent position and sitting position of patients in fiber bronchoscopy examination[J];中国现代医生;2014-32
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved