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《Journal of Zhejiang University(Natural Science)》 1999-01
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Study of noninvasive detection of coronary artery disease based on the application of wavelet transform to heart sounds

YE Xue song 1,CHEN Yu quan 1,LU Wei xue 1 CHEN Jun zhu 2,QIU Guo song 2,HU Xiao sheng 2(1.Dept. of Bioscience & Medical Engineering, Zhejiang Univ.Hangzhou 310027,China; 2.The First Affiliated Hospital to Zhejiang Univ.Hangzhou 310031,  
This paper studied the surface acoustical field of body's chest and the blood flow dynamics in coronary artery and then provided a new method to detect early coronary artery disease(CAD)which was based on the application of wavelet transform to whole cycle's heart sounds from multi channel.This system developed a highly sensitive heart sounds sensor array specially designed for detecting signals from various parts of thorax of normal persons and CAD patients.After pretreated,the high frequency signals in heart sounds were sampled by computer.The method of signal's wavelet transform was fit for the analysis of heart sounds because of its localization analysis both in frequency domain and in time domain.By comparing the analysis results of normal persons with abnormal persons,it could draw a conclusion that in every heart active cycle the average power ratio of the whole cycle's heart sounds to the diastolic period's heart sounds at different frequency segments was associtaed with coronary artery occlusion, moreover,the wavelet transform of the signals also provided the intensity of the changes in heart sounds of diastolic period which was due to the blood turbulence through the narrow coronary arteries.It has been proved by clinical practice that the method of wavelet transform of heart sounds provided a good manner to diagnose CAD and have a potential possibility for early detection of CAD.
【Fund】: 浙江省自然科学基金
【CateGory Index】: R540.4
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