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《Chinese Medical Record》 2012-03
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The Effect and Efficacy of Telmisartan to Renin,Angiotensin Ⅱ,and Aldosterone of Patients with Hypertension

Guo Yili,Du Fenghe,Gong Hongtao*,Beijing Tiantan Hospital Affiliated to Capital Medical University,Beijing 100050,China  
Objective to investigate the effect of telmisartan on renin,angiotensin Ⅱ and aldosterone of patients with hypertension.Methods One hundred patients with mild to moderate hypertension were given telmisartan 80mg/d for eight weeks.The change of blood pressure,heart rate,renin,angiotensin Ⅱ and aldosterone before and after treatment are observed.Results After treatment with telmisartan,systolic and diastolic pressure of the patients were both obviously lower than basic titer(P0.01);the level of serum angiotensin Ⅱ was obviously increased(P0.01);the levels of aldosterone were significantly decreased(P0.01);the level of plasma renin activity was also obviously increased(P0.05).Conclusion Telmisartan is a new type of antihypertensive drug for its safe,effective,well tolerance and slight side-effect.
【CateGory Index】: R544.1
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