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《Chinese Medical Record》 2012-05
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The Experiences of Heart Transplantation Model of Rats

Guo Xiaoqiu,Liu Zhenhong,Zhu Jiqiao,Li Xianliang,Beijing Chaoyang Hospital Affiliated to Capital Medical University,Beijing 100020,China  
Objective This paper discussed rapid and stable construction method of rats' heart transplantation models.Methods Using improved Ono animal model,we placed heterotopic heart transplantation models in rats' heart,which aortic arch of donor anastomosed with aorta of receptor in belly,pulmonary artery of donor anastomosed with vena cavaof receptor.Results Through learning about a month,rats models stayed in stability over 95%;vascular anastomosis time was(25±5)min;the ischemic time was(38±6)min.We completed a group of experimental animal models per day.Conclusion The key of success was to keep training and pay attention to operation details.
【CateGory Index】: R654.2
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【Citations】
Chinese Journal Full-text Database 2 Hits
1 WANG Xiao-liang,PENG Zhi-hai(The First People's Hospital Affiliated to Shanghai Jiaotong University,Shanghai 200080,China);Comparison of Two Methods of Cardiac Transplantation in Rats[J];Laboratory Animal Science;2008-06
2 GAO Xu-hui, WANG Hao-fei, WANG Wu-jun, ZOU Xiao-ming. Department of Cardiothoracic Surgery, Nanfang Hospital, The First Military Medical University, Guangzhou 510515, China;Surgical technique of making heterotopic heart transplantation models in rats[J];The Journal of Practical Medicine;2004-05
【Co-citations】
Chinese Journal Full-text Database 3 Hits
1 LIU Zhihong SHEN Bing GONG Hua LIU Fabing ZHU Jie BAO Erdun QIU Jianxin FAN Yu Department of Urology,Shanghai First People's Hospital,Shanghai 200080;Lmproved Technique for Chronic Graft Vascular Disease in a Rat Cardiac Allograft Model[J];Chinese Journal of Clinical Medicine;2009-01
2 Department of Cardiothoracic Surgery, Nanfang Hospital, Southern Medical University(Guangzhou 510515) Gao Xuhui Wang Wujun Zou Xiaoming et al;The relation between the expression of CD28~+ T lymphocyte and the acute rejection in heterotopic heart transplantation rats[J];Shaanxi Medical Journal;2005-06
3 WANG Liping,LIU Yue,MENG Jia,et al Department of Geriatrics,the Second Affiliated Hospital,Harbin Medical University,Harbin 150086,China;Establishment of heterotopic abdominal heart transplantation model in rats[J];Chinese Journal of Multiple Organ Diseases in the Elderly;2010-04
【Secondary Citations】
Chinese Journal Full-text Database 2 Hits
1 CHEN Jian-feng, GAO Yi, SUN, Er-wei, WANG Shuang (Department of Organ Transplantation, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China);Modification of a rat heterotopic heart transplantation model[J];Journal of First Military Medical University;2001-09
2 ZHI Xingyi,ZHANG Mingkui,QIAO Chenhui Department of Cardiovascular and Thoracic Surgery,the First Affiliated Hospital,Henan Medical University,Zhengzhou 450052;An improved technique of heterotopic heart transplantation in rats[J];;2001-02
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