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《Chinese Medical Record》 2012-05
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Clinical Analysis of 65 cases with Multiple Primary Neoplasms in Advanced Age

Zhai Bing,Zhu Hongli*,Department of Geriatric Hematology,PLA General Hospital,Beijing 100853,China  
Objective To investigate the clinical characters of multiple primary neoplasms(MPN) in advanced age,and to improve understanding of MPN in the elderly.Methods Clinical data of 65 patients with MPN in advanced age were retrospectively analyzed.Results 472 elderly patients had malignant tumors,and among them 65 had MPN,accounting for 13.8%.The median age was 76 years old when the first tumors were diagnosed.The most common involved systems were respiratory,digestive,and urogenital system.The most common organs were lung,stomach and prostate.The most common solid tumors of histological results were adenocarcinoma,transitional cell carcinoma and squamous cell carcinoma.The median survival time was 69 months.There was no statistical significant for survival time between synchronous and metachronous multiple primary neoplasms.Duplex metachronous primary neoplasms had a median interval time of 88 months between the two neoplasms,and there was no statistical significant for survival time between the group which the interval time was over and even 5 years and the group less 5 years.Conclusion The incidence of MPN in the elderly was significantly increased,but the degree of malignancy is relatively lower,and patients mostly have long survival time.Therefore,MPN in the elderly should be given adequate attention and further investigation.
【CateGory Index】: R730.4
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