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《Chinese Medical Record》 2012-12
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Research on Text Mining of Stem Cell

Li Xiaoli,Library of People's Hospital Affiliated to Hubei Medical College,Shiyan 442000,Hubei Province, China  
Objective To analyze and judge the stem cell research hotspot and research trend with text mining technique.Methods Collecting bibliography information and judging co-word cluster to generate co-occurrence matrix and co-word clustering by stem cell literature retrieval from Jan 1,2003 to July 13,2012,based on Pubmed database.Results The analysis shows that stem cell therapy,transplantation and nervous stem cells have been high-frequency subject headings.Two clustered word groups of cell mutation and immune system no longer appear in research literature after 2008 while four clustered word groups,cellular differentiation,hematopoietic stem cells,bone marrow stem cells,stem cell regulatory factors,appear in the list of high-frequency subject headings.Conclusion Stem cell therapy,transplantation and nervous stem cells have been the research hotspots,and research on stem cells is heading from the basic and applied fields towards more complicated fields,such as cell differentiation,cell regulation,and cell transplantation.
【CateGory Index】: R329
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