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《Chinese Medical Record》 2018-06
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Evaluation of the Effect of the Gemcitabine Bladder Perfusion in the Treatment of the Non-Muscular Infiltrating Bladder Tumor

Wang Xuesong;Liu Zhen;An Kang;Liu Peng;Yao Lei;Liaoning Provincial People's Hospital;  
Objective To evaluate the safety and efficacy of bladder perfusion with gemcitabine in the treatment of non-muscular invasive bladder cancer.Methods From December 1,2016 to December 1,2017,128 cases of muscularis invasive bladder cancer were selected as the object of study,the 128 patients were divided into two groups,the treatment group 64 examples,gives the transurethral resection of bladder tumor(TURBT)plus gemcitabine treatment,control group 64 examples,giving TURBT plus HCPT treatment,compared two groups of patients' clinical indicators,the recurrence rate and adverse reaction rate.Results The time of indwelling catheter in the treatment group and the number of hospitalized days were similar to those in the control group.The high-risk recurrence rate of the treatment group was 10.94%,less than that in the control group,26.56%,P0.05.The adverse reaction rate was 7.81% in the treatment group and 9.37% in the control group,P0.05.Conclusion Combined with TURBT,bladder perfusion with gemcitabine does not increase the catheterization time and hospital stay,which can effectively reduce the recurrence rate of high-risk patients without increasing the incidence of adverse reactions,which is of clinical significance and application value.
【CateGory Index】: R737.14
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