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《Molecular Cardiology of China》 2011-01
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Progress of Clinical Research in Mesenchymal Stem Cell Therapy for Heart Failure

JIA Chao,WANG Qi-xin. The Affiliated Hospital of Medical College Qingdao University,Qingdao 266003,China  
Heart failure is the end phase of various cardiovascular diseases.Most cardiomyocytes belong to permanent cells,with limited regeneration.Now that drug therapy、intervention therapy and surgical therapy can recanalize the infarct-related coronary artery and relieve the occurrence or symptom of heart failure to some extents,but these methods can’t increase the number of cardiomyocytes,which is not satisfactory. To solve this problem,we should increase cardiomyocyte number and blood supply.With the rapid development of molecular biology, mesenchymal stem cells can be used as a drug to supply or repair injured cardiomyocytes directly or indirectly under specific microenvironment and cytokines. mesenchymal stem cell transplantation for heart failure can improve cardiac function and has become a research hotspot.
【Fund】: 青岛市科技发展计划课题项目(05-1-NS-73)
【CateGory Index】: R541.6
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