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《China Poultry》 2018-07
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Effects of Polypeptide on Serum Biochemical Index,Serum Antibody Level and Immune Organ Index of Broilers

ZHAI Ming;LI Yan;LI Yan;Center Hospital of Zibo City,Shandong Province Zhangdian District;Shandong Sci-Health Biotechnology Co.,Ltd.;  
This experiment was conducted to study the effects of polypeptide on serum biochemical index, antibody level and immune organ index of broilers in order to verify the ability of polypeptide in improving broilers′ immunity ability. A total of 40 000 one-day-age Cobb500 chicks were randomly allotted to two treatments with four replicate per treatment and 5 000 chicks per replicate. Broilers in the control group were inoculated Newcastle disease vaccine and H9 subtype avian influenza vaccine according to the original immunization and pharmacy program at 7, 14 and 21 days of age, respectively. Broilers in experimental group were inoculated the above vaccines at 7 days of age and fed with basal diet with 400 g/t polypeptide at 13 to 15 days of age and 300 g/t polypeptide at 20 to 22 days of age. The trial lasted for 28 days. The results showed that serum total protein, globulin content and the ratio of globulin and albumin in experiment group were increased significantly by 10.75%, 15.17%, 11.45%. Meanwhile, serum glutamic oxalacetic transaminase activity in experiment group was improved by 6.23%(P0.05). The antibody titers against Newcastle disease virus and H9 subtype avian influenza virus in experiment group were increased significantly by 19.89% and 6.97%than those of the control group(P0.05), respectively. And meanwhile the spleen index and the thymus index in experiment group were improved obviously by 17.05% and 11.89% compared with the control group(P0.05), respectively.It′s concluded that dietary polypeptide could improve serum biochemical index, antibody level and immune organ index of broilers.
【Fund】: 山东省重点研发计划项目(2016GSF121029);; 山东半岛国家自主创新示范区(ZCQ16104)
【CateGory Index】: S831.5
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