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Investigation of Irgafos 168 and Irganox 1010 Released from Infusion Sets

XIE Xin-yi;FANG Min;HUANG Zi-wei;Guangdong Medical Instruments Quality Surveillance and Inspection Institute;  
To develop the high performance liquid chromatography(HPLC) method for investigation of the dissolution of Irgafos 168 and Irganox 1010 in paclitaxel injection. Detection limits found for Irganox 1010 and Irgafos 168 were 0.38μg/ml and 1.58μg/ml. Recovery tested at 3 concentration levels were 109.9% and 81.0%.The method was simple, efficient and accurate and suitable for analysis of Irgafos 168 and Irganox 1010 in paclitaxel injection.
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