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《实用妇科与产科杂志》 1993-01
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Genetic counseling of 22 patients of balanced translocation carrier.

Shi Donghong Dept of Obstetrics and Gynecology Shandong Provincial Hospital,250021.  
Twenty-two cases of balanced translocation carrier from Aug 1982 to Dec 1991 were analysed.The results showed that the commonest reason for counseling was recurrent abortion accounting for 77.2% The second commonest reason was fetal death due to deformity(9.09%). Karyotype analysis showed that majority of the cases were Robertsonian translation(81.82%),among which 77.78% was nonhomologous,and 22.23% was homologous. Reciprocal translocation accouted for the rest 18.82%. The paper suggested that patients of homologous Robertsonian translocation should be sterilized,and,for the nonhomologous,amniotic cells from amniocentesis at the second trimester of pregnancy should be cultured to make the prenatal diagnosis.
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【References】
Chinese Journal Full-text Database 2 Hits
1 .Shi Donghong; Chen Yanqin; Liu Xinmin, et al(Shandong Provincial Hospital, 250021);Human chromosome analysis for 502 cases of couples whose wife suffered from recurrent spontaneous abortions[J];CURRENT ADVANCES IN OBSTETRICS AND GYNECOLOGY;1994-02
2 Yu Liming; Lili; Li Jichun; Ding Yonghui(Dept.of Gynecology and Obstetrics,Affiliated Hosp.,Ningxia Med.Coll.);STUDY ON CYTOGENETICS OF 160 COUPLES WITH NATURAL ABORTION[J];NINGXIA MEDICAL JOURNAL;1996-03
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