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Preliminary evaluation of diagnosing malignant tumors by CRP assay in gynecologic field

Liu Guobing Gynecologic Department,Nan Fang Hospital Affiliated to the First Military Medical University,Guangzhou 510515.  
Serum C-reactive protein (CRP) was detected in 51 patients with benign gynecologic tumors nd 32 patients with malignant tumors. The results indicated that the sero-CRP level was obviously increased in patients with malignant tumors, but negative in patients with benign tumors. The CRP level reflected the severe degree of malignant tumors. The higher the CRP level was, the later the stage of malignant tumors would be. The detective rate of CRP in patients with ovarian carcinoma was 100%. But in 3 cases with malignant hydatidiform mole, the CRP was negative. Our results suggested that CRP assay was helpful in the diagnosis and prognasis of malignant gynecologic tumors, in differential diagnosis between benign and malignant tumors, and in forcasting the effect of chemotherapy in malignant tumors.
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