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Clinical observation on congenital adrenocortical hyperplasia:Analysis of 31 cases.

Xiao Fengyun The First Affiliated Hospital of Haerbin Medical University,150001.  
Thirty patients with congenital adrenocortical hyper- plasia(CAH)were treated with oral prednisoione and external genital organ orthomorphia.According to Pracler's classification of the abnormality of the exter- nal genital organs,5 cases were of type Ⅰ.,9 were of type Ⅱ,and the rest 17 were of type Ⅲ.All of the t patients had primary amenorrhea except for one whose mensis was normal.Breast were not well de- veloped resembling those of males.Dexamethasone in- hibition tests were performed before the treatment, and doses of prednisolone were given according to the urinary levelof 17-ketosteroid before the test.Sec- ond sexual signs were improved and menstruations oc- curred in all the patients after the treatment.Eleven of them were married.Six became pregnant.Four had term deliveries with healthy babies.Some of the pa- tients still maintained normal menstrual cycles after the cessation of the medication.The paper also dis- cussed whether CAH patients needed life long medica- tion.
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