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《Chinese Journal of Practical Gynecology and Obstetrics》 1995-01
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Intraheptic Cholestasis during Pregnancy:Clinical Analysis of 443 Cases.

Tan Yuedi.Department of Obstetrics and Gynecology,Central Hospital of Putuo District,Shanghai,200062.  
Totally 12716 pregnancies were delivered in our hopi- tal from January 1987 to September 1993.Among them,443 patients had intraheptic cholestasis of preg- nalcy(ICP)accounting for 3.48% of the pregnan- cies.The main clinical features of ICP were skin irrita- tion,jaundice,and increased serum glutamic-pyruvic transaminase.Eighty-five of the 443 patients had premature labour,accounting for 19.2%.Thirteen had fetal death,8 had stillbirth,and three had neona- tal death.The perinatal mortality was 5.42%.Forty -eight babies had an Apgar score 7 or less,account- ing for 10.8%.Average neonatal weight was 3082 gm.The author suggested that early diagnosis of ICP and intensive monitoring of fetal heart and amniotic fluid during pregancy and labour and prompt treat- ment may reduce the occurrence of complications of ICP.
【CateGory Index】: R714.2
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