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《Chinese Journal of Microecology》 1989-01
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Change and Translocation of Indigenous Enteric Bacteria from Gl Tract of Rats after Burn

Yu Yong, et al.,304 Hospital, Beijing 100037  
In this study, A quantitative analysis in 7 species indigenous enteric bacteria and culture of blood, viscerae were made. The pathological change of the wall of GI tract in rats which were injected intraperitoneally 80mg/kg dexamethasone (DXM) (a drug of immunity-inhibitor) after burn were observed. In the group of burn(B)and the group of injection DXM only (I), the pathological changes of the wall of GI tract were slight, the population level of enteric bacteria showed no obvious alteration and the rate translocation of indigenous enteric bacteria were low. In the group of burn plus DXM (B+I), the pathological changes of the wall of GI tract and the population level of enteric bacteria appeared more serious than those in the group B and I. The significant increases of enteric bacilli population levels in the contents of ileum, cecam, and colon and the significant decrease of bacteroides population level in ileum were disclosed. The rate of translocation of enteric bacteria were found to increase up to 60%. On the other hand, a number of rats in tlle group BI and I presented endogenous infection of either Corynehacterium or both Corynebacierium and Enteric bacillus. From the findings of the differences found in the pathological changes, alteration of bacterial population level and physilogical function in different segments of GI tract, we assume that ileum and those segments of GI tract above ileum might be the main locality of enteric bacteria translocation.
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1 a Nuo shan;Chang Guo you;Yu Yong(Experimental Department,304 hospital of PLA)[;Observation of intestinal flora of SPF mice in the different immune function[J];LABORATORY ANIMAL SCIENCE AND ADMINISTRATION;1996-01
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