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《Chinese Journal of Microecology》 1989-01
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The Relationship between Clostridium difficile Enteroc olitis and Intestinal Dysbacteriosis

Chen tun-long, et al., Department of Gastroenterology, Nanfang Hospital, First Military Medical Colleage, Guangzhou 510515  
A total of 11 faecal specimens of Clostridium difficile-associated colitis (CDEC) were analysed for the contents of 10 microflora, and the results were compared with the flora of 20 cases with different causes other than CDEC diarrheal patients (casecontroll)and 22 health adults(health-controll)during April 1988 to March 1989. The results showed that the numbers of E. coli and Bifidobacteria in CDEC patients were found lower tban those in controlls, suggesting that the decrease of these two bacteria played an important role in the development of CDEC. The numbers of other bacteria were close to those in controlls. Moreover, we analysed the frequency of various antihiotics used in CDEC patients. The antibiotics at risk have been found to be ampicillin, cephalosporin and gentamycin.
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