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《CHINESE JOURNAL OF MICROECOLOGY》 2000-01
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DETERMINATION OF ACTIVATIONS OF ANTIBIOTICS IN PROSTATES OF PATIENTS WITH CHRONIC PROSTATITIS

Wang He, Chen Zhenghong, Zhang Li, et al. (Department of Microbiology, Gui yang Medical College, Guiyang 550004)  
To determine the penetrability of antimicrobial drugs to prostatic tissue of patients with chronic prostatitis and probe the feasibility of cure of the prostatitis by the routine ways and methods,oral,intramuscular injection or intravenous injection,with antimicrobial drugs,the quantity and properties of the microoganisms and the activities of the drugs in the prostatic liquids and change of the symptome of the patients befor and after treatment with the antimicrobial drugs according to the results of the sensitive test were observed.The results were showed that the pathogens including bacteria spp., mycoplasma spp., fungi spp., and chlamydia could be isolated separatly from the prostatic liquids of 185 cases of patients with chronic prostatitis and in which the Gram positive bacteria were commonest. The microoganisms, by the results of sensitive tests to antimicrobial drugs,would be removed completely after treatment by either oral,intramuscular injection or intravenous injection and the symptoms of the patients,following disappearance of the microoganisms,would be disappeared of relaxed rematkablely. The determinable activeties of some of the antimicrobial drugs would be found after 30 minutes of the drug was gave and some of them would be kept more than 36 hours in the prostatic fluids. It was showed that most kinds of antimicrobial drugs which were gave by the routine ways and methods would penitrate the prostatic tissues of the patients with chronic prostatitis and arrive a concentration of removing the pathogens in the protates and cure effectively the diseases. It would be the crux to cure the prostatitis that exactitude of pathogenic diagnosis and tational use of antimicrobial drugs,but it would have nothing to do rematkablely with the kinds of antimicrobial drugs and the ways or methods of treatment.
【Fund】: 贵州省卫生厅基金
【CateGory Index】: R697.3
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