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《Chinese Journal of Microecology》 2008-01
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Homogeneous analysis of epidemic strains of multidrug-resistant Acinetobacter baumannii

CHEN Hui-hong1,SHEN Bo,WANG Yi-man,YU Yun-song,YU Su-fei,DAI Dong-ling,ZHOU Jun,FU Ying,CHEN Pei-zhen,YU Wen-xian(Taizhou Hospital,Taizhou 317000,China)  
Objective To investigate the drug resistance,the homology and the carbapenemases gene type of the multi-drug resistant Acinetobacter baumanii(MDR-AB) strains isolated from inpatients in ICU and SICU of our hospital during January 2006.Methods VITEK-60 system was used to identify 8 MDS-AB strains isolated from inpatients at ICU and SICU during January 2006.Then antibiotics,such as cephalosporins,aminoglycosides,quinolones and carbopenems,were applied to test the 8 strains' susceptibility with VITEK-60 system except for cefoperazone/sulbactam and meropenem that were experimented by K-B method.PCR was carried out to amplify the carbapenemase genes and identify the DNA typing of the 8 strains.Results The 8 strains were sensitive to cefoperazone/sulbactam and expressed highly resistant to cephalosporins,aminoglycosides,quinolones and carbopenems.The 8 strains came from the same gene typing:that was OXA-23.PFGE confirmed the 8 strains were the same one clone.Conclusion One clone of MDR-AB had led to partly prevalence in our hospital.The carbapenemase genotype of this strains is OXA-23.
【CateGory Index】: R446.5
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