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《Chinese Journal of Microecology》 2008-06
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The study of antagonistic activity of Lactobacillus casei LC2W against Helicobacter pylori SS1 for adhesion to MKN-45 cells by mathematical models

ZHOU Fang-fang,WU Zheng-jun,WANG Yin-yu,GUO Ben-heng (The Technique Center of Bright Dairy & Food Co.,Ltd,Shanghai 200072,China)  
Objective To study the antagonistic activity of Lactobacillus casei LC2W against Helicobacter pylori SS1 for adhesion to MKN-45 cells and explicate the phenomena of bacterial adhesion and inhibition.Methods Gastric-cell line MKN-45 was cultured in vitro,plate counting was used to study the adhesive ability of the two strains;mathematical models based on a simple dissociation process were developed and the competition,exclusion and displacement between the two strains were compared according to the models.Results The equations obtained from the models allow the estimation of the maximal number of LC2W and Helicobacter pylori SS1 cells that could adhere to MKN-45 cells respectively;they also characterized the affinity of the bacteria to MKN-45 cells and the theoretical adhesion ratio of two bacteria present in a mixed suspension.The results showed that there were significant competition and elimination of Helicobacter pylori SS1 by LC2W,both of which were dependent on concentration of LC2W;the displacement of Helicobacter pylori SS1 by LC2W was insignificant or slow.Conclusions The mathematical models were suitable for simulating the adhesion and the antagonistic activity of LC2W against Helicobacter pylori SS1 for adhesion to MKN-45 cells,which meant the antagonistic activity was mainly attributed to the competitive space occupying between the two strains.
【CateGory Index】: R371;R735.2
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【References】
Chinese Journal Full-text Database 2 Hits
1 CAO Zhen-hui;LIU Yong-shi;PAN Hong-bin;TIAN Rui-jiao;GU Da-hai;LI Shu-ying;XU Yong-ping;LIN Qiu-ye;Yunnan Provincial Key Laboratory of Animal Nutrition and Feed Science;Faculty of Animal Science and Technology,Yunnan Agricultural University;College of Food Science and Technology,Yunnan Agricultural University;Post-doctoral Research Workstation Dalian SEM Bio-Engineering Technology Co.,Ltd.;School of Life Science and Technology,Dalian University of Technology;;Research progress of Lactic acid bacteria on the probiotic properties and mechanisms[J];食品工业科技;2015-24
2 LV Zhi-fa,XIE Yong.The First Affiliated Hospital of Nanchang University,Nanchang 330006,China;Development of Probiotics Adjuvant Therapy on Infection of Helicobacter Pylori[J];中国全科医学;2013-23
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LIU Shao-min 2,MAN Chao-xin 1,LI Li 2,JIANG Yu-jun 1,2(1 National Research Center of Dairy Engineering and Technology,Northeast Agricultural University,Harbin 150086,China;2 Key Lab of Dairy Science,Ministry of Education,College of Food Science and Engineering,Northeast Agricultural University,Harbin 150030,China);Research on Immunomodulatory of Lactic Acid Bacteria[J];中国食物与营养;2013-04
2 Maramnisa·Amar,W·Yimit,A·dolkun,D·Mamatyusuf*(College of Life Sciences and Technology,Xinjiang University,Urumqi 830046,China);Selection of high-efficiant antibacterial intestinal lactic acid becteria[J];食品工业科技;2012-24
3 GU Yue-hua,ZHANG Jing-sheng,AN Hao-ran,HAO Yan-ling (College of Food Science & Nutritional Engineering,China Agricultural University,Beijing,100083,China);Screening of β-galactosidase highly producing Lactobacillus plantarum and its enzymatic properties[J];中国乳品工业;2012-09
4 ZHAO Dong,XU Guifang,ZOU Xiaoping.Department of Gastroenterology,The Affiliated Drum Tower Hospital of Nanjing University Medical School,Nanjing(210008);Modulatory Effect of Probiotics on Gastric Mucosal IL-8,IFN-γ and IL-4,IL-10 Levels in Helicobacter pylori-infected C57BL/6 Mice[J];胃肠病学;2012-05
5 ZHOU Xiao-ying,CHEN Xiao-lin(College of Life Science,Anhui Agriculture University,Hefei 230036,China);The beneficial function of Lactic acid bacteria and research progress in its application[J];中国微生态学杂志;2011-10
6 LI Lan-fang(Pediatric Department,People′s Hospital of Chibi,Chibi 437300,China);Effect of probiotics on feeding intolerance of premature infant[J];海南医学院学报;2011-06
7 SONG Yuan-liang,LI Hai-yan,LIU Chen-jian(Laboratory of Applied Microbiology,Faculty of Life Science and Technology,Kunming University of Science and Technology,Kunming 650224,China);Progress in studies on treatment of lactose intolerance with Lactic acid bacteria[J];中国微生态学杂志;2010-08
8 ZHOU Fang-fang,WU Zheng-jun,WANG Yin-yu,GUO Ben-heng (The Technique Center of Bright Dairy & Food Co.,Ltd,Shanghai 200072,China);The study of antagonistic activity of Lactobacillus casei LC2W against Helicobacter pylori SS1 for adhesion to MKN-45 cells by mathematical models[J];中国微生态学杂志;2008-06
9 Chao Zhou, Feng-Zhen Ma, Xue-Jie Deng, Hong Yuan, Hong-Sheng Ma, Department of Gastroenterology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China;Lactobacilli inhibit interleukin-8 production induced by Helicobacter pylori lipopolysaccharide-activated Toll-like receptor 4[J];World Journal of Gastroenterology;2008-32
10 Yan Jixian, Li Mingyue, Zhong Jingyao, Xie Yiying (Bao Gang Hospital Affiliated to Shanghai Second Medical University, Shanghai);AN INVESTIGATION OF THE ABSORPTION AND INTOLERANCE OF LACTOSE IN MILK AND YOGURT IN NORMAL ADULTS[J];营养学报;1987-02
【Secondary References】
Chinese Journal Full-text Database 9 Hits
1 SHU Wenxiu;WU Zufang;LIU Lianliang;WENG Peifang;Key Laboratory of Applied Marine Biotechnology, Ministry of Education, School of Marine Sciences,Ningbo University;;Volatile Flavor Compounds of Fermented Grapefruit Juice with Probiotics[J];食品科学;2018-04
2 CHEN Jia;DENG Yuan-xi;ZHANG Bin;LIU Deng-yong;XU Hui;Department of Food and Bioengineering,Bengbu College;Meat Science and Technology Institute,Bohai University;;Effect of CLA producing Lactobacillus on gut immune function in mice[J];食品科技;2017-04
3 CHEN Shujun;SHI Yue;HU Jie;XU Xiaoxia;LI Le;ZHANG Junmei;LI Jiayi;WANG Cuilian;College of Life Science,Shanxi University;;Process Optimization by Response Surface Methodology for the Development of a Beverage Based on Lactic Acid Fermentation of Quinoa Malt[J];食品科学;2017-16
4 ZHANG Penghai;ZHU Peizhen;CHEN Yinqiao;MA Min;LV Yuke;LI Ke;Department of Oncology,Yongkang First People's Hospital in Zhejiang Province;;Clinical control research on micro ecological nutrition intervene in tumor dyscrasia[J];中国现代医生;2017-07
5 Hang Yu;Shou-Chao Zhu;Shuo-Gui Xu;Department of Emergency Medicine, Shanghai Changhai Hospital;;Value of Bifico in rescue therapy for Helicobacter pylori eradication[J];世界华人消化杂志;2016-13
6 CHENG Xiaona;HU Yangqian;Dongfeng General Hospital Affiliated to Hubei Medicine College;;The investigation of expression levels of IL-10,TNF-α of different types of bacteria Helicobacter pylori infection in patients with peptic ulcer[J];河北医药;2016-08
7 SHENGYu qi;HUANG Yi-hua;XING Yuan;YU Li-jun;Health Clinic,Haikou Garrision of PLA;Department of Digestive Internal Medicine,the 187th Hospital of PLA;;Clinical study of clostridium butyricum combined with quadruple therapy for Helicobacter pylori eradication[J];临床消化病杂志;2016-02
8 ZHANG Lin;Spleen and Stomach Department,Hubei University of Chinese Medicine Affiliated Xiangyang Hospital;;Comparison on the clinical curative effects of the sequential therapy and triple therapy in the eradication of Helicobacter pylori[J];临床消化病杂志;2015-05
9 CHEN Jing;Department of Neonatology,First People's Hospital of Ziyang City;;Change of serum and colon lavage fluid related indicators after probiotics combined with zinc preparations treatment for persistent diarrhea in children[J];海南医学院学报;2015-11
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