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《Chinese Journal of Microecology》 2009-01
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Effect of isomalto oligosaccharide on intestinal flora,serum IgG and intestinal mucous sIgA of D-galactose-induced aging rats

WANG Chun-min1,LI Li-qiu1,REN Ji-qiu1,DAI Yue2,MA Shu-xia1(1.Department of Microbiology,Jiamusi University,Jiamusi 154007,China;2.Department of Parasitology,Jiamusi University,Jiamusi 154007,China)  
Objective To explore the effect of isomalto oligosaccharide on the function of intestinal mucous of the D-galactose-induced aging rats.Methods Wistar rats were randomly divided into three groups,young control group,aging model group and Isomalto oligosaccharide treated group.The model of D-galactose-induced aging rat was established;Isomalto oligosaccharide was given by intragastric application for 30 days.The intestinal flora,serum IgG and intestinal mucous sIgA were measured for every group.Results Dysbacteria could be observed in aging rats;After intragastric application with Isomalto oligosaccharide,the number of Bifidobacteria was increased(P0.05);the number of Bacterium coli and Enterococcus were decreased(P0.05);the level of serum IgG and intestinal mucous sIgA were increased(P0.05).Conclusion The function of intestinal mucous in the D-galactose-induced aging rats can be improved by Isomalto oligosaccharide.
【Fund】: 佳木斯大学课题(S44)
【CateGory Index】: R96
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