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《Chinese Journal of Microecology》 2009-01
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The therapeutic effects of Ataining on chronic colitis

SONG Jie1,PEN Li-hua1,ZHANG Min1,NIE Zhao-hua1,WEN Jing1,WAN Fu-chang2,LI Hong-fu2,CUI Yun-long2(1.Department of Digestion,No.261 Hospital of PAL,Beijing 100094,China;2 Qingdao Center of Micro-ecology Engineering Technology Research,Qingao 266400,China)  
Objective To evaluate the therapeutic effect of Ataining through the clinical treatment of IC and UC to find a new way to treat these diseases.Methods 21 cases of patients with IC and UC(the diagnosis of UC was according to the UC diagnostic criteria of Cooperative Group of Gastroenterology Branch of the Chinese Medical Association)were chosen and treated with Ataining,three capsules each time and three times daily for 4~8 weeks.The improvement of their symptoms during treatment were observed and the therapeutic effect after treatment was evaluated by colonoscope rechecking.Results The diarrhea frequency of patients were reduced significantly from(3.60±0.94)times/d before treatment to(1.5±0.71)times/d after treatment(P0.001);mucus stool and bloody stool were reduced significantly from 100% to 9.5%;abdominal pain was relieved from 90.5% to 14.3% and tenesmus from 66.7% to 9.5%.According to the results of colonofiberscopic examination,there were 10 cases had mucosal healing(47.6%);8 cases got improved in mucosa(38.1%);while 3 cases had no changes(14.3%).The total effective rate was 85.7%,with 10 cases of complete remission(47.6%),8 cases had effective(38.1%),and 3 cases ineffective(14.3%).In 12 cases of UC,there were 6 cases of complete remission(50%),4 cases effective(33.3%),2 cases ineffective(16.7%);the total effective rate was 83.3%.Conclusion Ataining had considerable therapeutic effects on IC and UC.It could improve clinical symptoms of UC and restore the scathed intestinal mucosa.
【CateGory Index】: R574.62
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