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《Chinese Journal of Microecology》 2009-01
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Analysis of the pathogenic micro-organisms in venous catheter related infections

LIAO Kang1,FENG Pin-ning1,WANG Hai-ying2,CHEN Qiu-gang1,CUI Yin-peng1(Department of Laboratory Medicine1,Surgery2,The First Affiliated Hospital of Sun Yat-sen University,Guangzhou 510080,China)  
Objective To investigate the distribution and antimicrobial susceptibility testing of the pathogenic micro-organisms of venous catheter related infections.Methods All of the 106 samples' laboratory data from 2006 to 2007 with venous catheter related infections in The First Affiliated Hospital of Sun Yat-sen University were analyzed retrospectively.Results Total of 106 strains were isolated from all venous catheter specimens,of which 53 strains(50%)were Gram-positive cocci,33 strains(31.1%)were gram-negative bacilli,and 16 strains(15.1%)were fungi.The most common pathogens in Gram-positive cocci were coagulase negative Staphylococci(CNS)(31.1%)and Staphylococcus aureus(11.3%)Methicillin-resistant staphylococcus aureus(MRSA)accounted for 75% and methicillin-resistant coagulase negative staphylococci(MRCNS)accounted for 87.9 % in cocci infection.Acinetobacter baumannii was 9.4% and Pseudomonas aeruginosa was 6.6% in gram-negative bacilli;Candida albicans was 4.7% and Candida tropicalis was 3.8% in fungi.Gram-positive cocci were very sensitive to Vancomycin,Linezolid and Teicoplanin.Gram-negative bacilli were more sensitive to Cefoperazon/Sulbactam,Meropenem,Imipenem and amikacin than to other drugs and the resistance rate was 5%,9.1%,14.8% and 15.4% respectively.Conclusions The most common pathogens in venous catheter related infections were coagulase negative Staphylococci(CNS)and all isolated becteria showed a serious resistance to most antibiotics.Properly use of antibiotics is very necessary.
【CateGory Index】: R446.5;R401
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