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《Chinese Journal of Microecology》 2012-01
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Effect of isomalto oligosaccharide on intestinal mucosal immunity of aging model mice

WANG Chun-min1,MA Shu-xia1,TONG Li-bo2,HAN Gui-hua2,CUI Gang1,OU Qin3(1.Department of Microbiology,Jiamusi University,Jiamusi 154007,China;2.The First Affiliated Hospital of Jiamusi University,Jiamusi 154002,China;3.Department of Biochemistry,Jiamusi University,Jiamusi 154007,China)  
Objective To explore the modulating function of isomalto oligosaccharide on intestinal mucosal immunity of aging model mice and its possible mechanisms.Method 48 Kunming mice were randomly divided into 4 group: young control group,aging model group,IMO group and IMOLCM group.After the aging models were made by injection of D-galactose,the IMO group was given IMO while IMOLCM group was given IMO and lincomycin.Each group were killed after 30 days.We detected the quantity of intestinal flora by the method of quantitative detection;the level of sIgA of intestinal mucous membrane by the method of radioimmunity;the expression of the IgA+ plasma cell in mice′s intestinal mucous membrane by the immunohistochemical method.Result(1) Dysbacteria could be observed in aging mice;The level of sIgA of intestinal mucous membrane,IgA+ plasma cell in aging model group were lower than the young control group′s;(2) Dysbacteria had improwed in IMO group;The level of sIgA of intestinal mucous membrane,the number of IgA+ plasma cell in IMO group were higher than the aging model group′s(P0.05);(3) Dysbacteria could be observed again in IMOLCM group;The level of sIgA of intestinal mucous membrane,the number of IgA+ plasma cell in IMOLCM group were lower than the IMO group′s(P0.05).Conclusion(1) IMO can improve dysbacteriosis of aging model mice and enhance the function of intestinal mucosal immunity.(2) That IMO can improve immunity may come true mainly by increasing the number of probiotics.
【Fund】: 黑龙江省卫生厅科研项目(2010-481)
【CateGory Index】: R-332
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【References】
Chinese Journal Full-text Database 1 Hits
1 WANG Shao-guang~1,ZHANG Xiao-feng~1,HAN Ping~1,YIN Feng-ke~1, WANG You-li~1,HUANG Run-ping~1,LIU Yan~1 (1.College of Public Health,Zhengzhou University,Zhengzhou 450001,China; 2.Center for Disease Control and Prevention in Zhongyuan District of Zhengzhou City Henan Province,Zhengzhou 450001,China);EFFECTS OFOLIGO-ISOMALTOSE ON INTESTINAL FLORA OF MICE AND METABOLIC PRODUCTS THEREOF[J];Journal of Henan University of Technology(Natural Science Edition);2012-05
【Citations】
Chinese Journal Full-text Database 4 Hits
1 FAN Jun (Digestive Institute,The First Affiliated Hospital of Nanchang University,Nanchang 330006,China);Intestinal Mucosal Immunity[J];International Journal of Immunology;2006-02
2 ;Progress in Isomaltooligosaccharides Research and Their Application Prospect[J];Cereal & Feed Industry;2002-03
3 ZHAO Jin,WANG Jiao,KAN Jian-quan*(Food Science College,Southwest University,Chongqing 400716,China);THE STUDY OF ISOMALTO OLIGOSACCHARIDE'S PHYSIOLOGICAL FUNCTION AND THE APPLICATION[J];Food Research and Development;2007-02
4 Yang Dongsheng (Bio_engineering staffroom of Technology College, Hainan University,Haikou 570228);Researching of Bifidobacterium and Bifidus-Factors[J];China Food Additives;2004-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 JIN Guang ming 1,YANG Qian 2,LIU Shen bin 2 (1.Anhui Technical Teachers College,Fengying 233100,China 2.College of Veterinary Medicine,Nanjing Agricultural University,Nanjing 210095,China);Animal Mucosal Immunization and Secretory Immunoglobulin A(SIgA)[J];Journal of Anhui Technical Teachers College;2003-02
2 WU Shu-qing1,WANG Shun-yu2,TAN Ke1,LI Rong-he1(1.Food Science and Engineering Department,Changchun University,Changchun 130022,China;2.College of Biological and Environmental Engineering,Zhejiang University of Technology,Hangzhou 310032,China);Studying progress of Bifidobacteria[J];Journal of Changchun University;2007-08
3 YI Xue-jing1,2 reviewing,LU Si-ping2,LI Qiong3 checking(1.College of Biosicence and Biotechnoloty,Hunan Agricultural University,Changsha 410128,Hunan,China;2.Department of Preclinical Medicine,Yueyang Vocational Technical College,Yueyang 414000,Hunan,China;3.Bureau of Animal Husbandry and Aquaculture,Yongxing County,Chenzhou 423300,Hunan,China);Intestine health and metabolism of conditionally essential amino acids[J];Parenteral & Enteral Nutrition;2009-01
4 ;ADCC效应综述[J];Contemporary Medicine;2011-34
5 Li Hong,Su Min,Yang Yu,Hu Rong,Huang Yue,Xu Tingliang,Jiang Fengrong (Department of Histology and Embryology,Guiyang Medical University,Guiyang,Guizhou Province,550004,China);Histogenesis of lymphoid tissue and development of T and B lymphocytes in human fetal appendix[J];Acta Academiae Medicinae Militaris Tertiae;2010-16
6 Hu Rong,Su Min,Huang Yue,Li Hong,Jiang Fengrong,Xu Tingliang(Department of Histology and Embryology,Guiyang Medical College,Guiyang,Guizhou Province,550004,China);Genesis of lymphoid tissue and development of IgM-positive B cells in human fetal ileum[J];Journal of Third Military Medical University;2011-05
7 XU Puwen LI Yuanxiao PANG Youzhi (College of Animal Science and Technology,Henan University of Science and Technology,Luoyang 471000,China);Fermented Liquid Feed:Effects on Weaner Piglet Intestinal Health[J];Chinese Journal of Animal Nutrition;2011-12
8 ZHU Cui1,2,JIANG Zong-yong1(1.Guangdong Key Laboratory of Animal Breeding and Nutrition,Guangdong Public Laboratory of Animal Breeding and Nutrition,The Key Laboratory of Animal Nutrition and Feed Science(South China) of Ministry of Agriculture,State Key Laboratory ofLivestock and Poultry Breeding,Institute of Animal Science,Guangdong Academy of Agricultural Sciences,Guangzhou 510640;2.College of Animal Science,South China Agricultural University,Guangzhou 510642,China);Regulative Function of Glutamine on Intestinal Mucosal Immunity in Early-weaning Piglets[J];China Animal Husbandry & Veterinary Medicine;2011-08
9 ZHU Cui1,2,SHI Zi-biao1,3,JIANG Zong-yong1,WANG Li1(1.Guangdong Public Laboratory of Animal Breeding and Nutrition,Key Laboratory of Animal Nutrition and Feed Science in South China,Ministry of Agriculture,P.R.China,State Key Laboratory of Livestock and Poultry Breeding, Institute of Animal Science,Guangdong Academy of Agricultural Sciences,Guangzhou 510640,China; 2.College of Animal Science,South China Agricultural University,Guangzhou 510642,China; 3.School of Life Sciences,Sun Yat-Sen University,Guangzhou 510006,China);Roles of Lactobacillus in Regulating Intestinal Barrier Functions[J];China Animal Husbandry & Veterinary Medicine;2012-09
10 YUE Min-jie1,SHI Yuan-yuan1,FU Shuai-gu1,WANG Yan-bin1,KANG Xiang-tao1,2(1.College of Animal Science and Veterinary Medicine,Henan Agricultural University,Zhengzhou 450002,China; 2.Henan Innovative Research Center for Poultry Germplasm Resources,Zhengzhou 450002,China);Research Progress of Bacillus subtilis as Drug and Immunogen Delivery Carrier[J];China Animal Husbandry & Veterinary Medicine;2013-04
China Proceedings of conference Full-text Database 2 Hits
1 QIAO Shi-yan MAO Xiang-bing WANG Wei-wei (College of Animal Science and Technology,China Agricultural University,Beijing,100193,China);Research Adavances of Amino Acids on the Function of Intestinal Barrier for Pigs[A];[C];2008
2 LIU Peng-fei,ZHONG Xiu-hui (College of Animal Science and Veterinary Medicine,Agricultural University of Hebei,Baoding,071001);Effect of MaXingShiGan Powder on IgA Secreting Cells of chicken Bronchus[A];[C];2010
【Co-references】
Chinese Journal Full-text Database 2 Hits
1 CHENG Dong DING Limin~* LIU Danli(College of Animal Science and Technology, China Agricultural University, Beijing 100193, China) associate professor;Effects of Oligosaccharides on Intestinal Flora, Diarrhea and Fecal Quality in Tibetan Mastiff Puppies[J];Chinese Journal of Animal Nutrition;2009-05
2 HU Xue-zhi(Shanghai Institute of Microbiology Research,Shanghai,200000);The relation of functional oligosaccharide and intestinal health[J];Jiangsu Condiment and Subsidiary Food;2011-02
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 JIANG Xiuju,LUO Yu The First People's Hospital of Xinxiang City, Xinxiang 453000,China;Application of Isomalto-oligosaccharides Used in Children with Functional Dyspepsia[J];Journal of Medical Forum;2005-10
2 Bi Jinfeng, Wei Baodong, Li Changbiao;Application of Isomaltooligosaccharide in Bread[J];Cereal & Feed Industry;2004-08
3 ;The Functions and Industrial Development of IsomaltoOligosaccharide[J];CEREAL & FEED INDUSTRY;1999-04
4 WANG Fang-an,et al;Study on the fanctional beverage with Dichotomofactor of oligosaccharides of isomaltose[J];Liquor-making;2002-03
5 Yue Zhenfeng Chen Xiaoxia Peng Zhiying (The College of Food Engineering and Biotechnology, South China University of Technology, Guangzhou, 510641);Status Quo and Advance of Research on α Glucosidase[J];FOOD AND FERMENTATION INDUSTRIES;2000-03
6 Yue Zhenfeng Peng Zhiying Xu Jianxiang Zhao Mouming Zhang Zhixu(The College of Food Engineering and Biotechnology,South China University of Technology, Guangzhou, 510640);Immobilization of α-Glucosidase on Chitosan[J];Food and Fermentation Industries;2001-04
7 Chen Bicheng Hu Zhixiang (Institute of Microbiology Academia Sinica, Beijing, 100080);Studies on Isomalto oligosaccharides Production by Transglucosidase (E. C. 2. 4. 1. 24) from Aspergillus cinamomeus Schiemann[J];FOOD AND FERMENTATION INDUSTRIES;1999-04
8 Jin Zonglian et al.;The Regulative Effect of Isomaltooligosaccharide On Intestinal Flora and Constipation of Mice[J];Food Science;2001-06
9 Zhao Kai;The Property of Isomaltooligosaccharide and Its Application in Low Sugar Ice Cream[J];Food Science;2003-01
10 Wang Xiaolan,Wei Dongzhi,Chen Shaoxin,et al. (State Key Laboratory of Bioreactor Engineering, ECUST,Shanghai China 200237);EFFECT OF GALACTOOLIGOSACCHARIDES ON GROWTH OF BIFIDOBACTERIA IN VIVO AND IN VITRO[J];CHINESE JOURNAL OF MICROECOLOGY;2000-01
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